End-to-end communication in the modulation of translation by mammalian RNA viruses

A 5′–3′ end interaction leading to stimulation of translation has been described for many cellular and viral mRNAs. Enhancement of viral translational efficiency mediated by 5′ and 3′ untranslated regions (UTRs) has been shown to occur via RNA–RNA interactions or novel RNA–protein interactions. Mamm...

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Detalles Bibliográficos
Autores principales: Edgil, Dianna, Harris, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172311/
https://www.ncbi.nlm.nih.gov/pubmed/16307817
http://dx.doi.org/10.1016/j.virusres.2005.10.012
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author Edgil, Dianna
Harris, Eva
author_facet Edgil, Dianna
Harris, Eva
author_sort Edgil, Dianna
collection PubMed
description A 5′–3′ end interaction leading to stimulation of translation has been described for many cellular and viral mRNAs. Enhancement of viral translational efficiency mediated by 5′ and 3′ untranslated regions (UTRs) has been shown to occur via RNA–RNA interactions or novel RNA–protein interactions. Mammalian RNA viruses make use of end-to-end communication in conjunction with both viral and cellular factors to regulate multiple processes including translation initiation and the switch between translation and RNA synthesis during the viral lifecycle.
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spelling pubmed-71723112020-04-22 End-to-end communication in the modulation of translation by mammalian RNA viruses Edgil, Dianna Harris, Eva Virus Res Article A 5′–3′ end interaction leading to stimulation of translation has been described for many cellular and viral mRNAs. Enhancement of viral translational efficiency mediated by 5′ and 3′ untranslated regions (UTRs) has been shown to occur via RNA–RNA interactions or novel RNA–protein interactions. Mammalian RNA viruses make use of end-to-end communication in conjunction with both viral and cellular factors to regulate multiple processes including translation initiation and the switch between translation and RNA synthesis during the viral lifecycle. Elsevier B.V. 2006-07 2005-11-22 /pmc/articles/PMC7172311/ /pubmed/16307817 http://dx.doi.org/10.1016/j.virusres.2005.10.012 Text en Copyright © 2005 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Edgil, Dianna
Harris, Eva
End-to-end communication in the modulation of translation by mammalian RNA viruses
title End-to-end communication in the modulation of translation by mammalian RNA viruses
title_full End-to-end communication in the modulation of translation by mammalian RNA viruses
title_fullStr End-to-end communication in the modulation of translation by mammalian RNA viruses
title_full_unstemmed End-to-end communication in the modulation of translation by mammalian RNA viruses
title_short End-to-end communication in the modulation of translation by mammalian RNA viruses
title_sort end-to-end communication in the modulation of translation by mammalian rna viruses
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172311/
https://www.ncbi.nlm.nih.gov/pubmed/16307817
http://dx.doi.org/10.1016/j.virusres.2005.10.012
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