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Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers

Detection of invading pathogens by pattern recognition receptors (PRRs) is crucial for the activation of the innate immune response. These sensors signal through intertwining signaling cascades which result in the expression of pro-inflammatory cytokines and type I interferons. Conjugation, or bindi...

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Detalles Bibliográficos
Autores principales: Oudshoorn, Diede, Versteeg, Gijs A., Kikkert, Marjolein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172403/
https://www.ncbi.nlm.nih.gov/pubmed/22964110
http://dx.doi.org/10.1016/j.cytogfr.2012.08.003