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Prokaryotic expression of antibodies and affibodies
Recent advances have been made in the development of systems for the display and expression of recombinant antibodies and affibodies in filamentous phages, Escherichia coli and other prokaryotic cells. Emphasis has been placed on improving phage and phagemid vectors, alternative systems for expressi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172615/ https://www.ncbi.nlm.nih.gov/pubmed/15296932 http://dx.doi.org/10.1016/j.copbio.2004.06.004 |
| _version_ | 1783524288825917440 |
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| author | Fernández, Luis Angel |
| author_facet | Fernández, Luis Angel |
| author_sort | Fernández, Luis Angel |
| collection | PubMed |
| description | Recent advances have been made in the development of systems for the display and expression of recombinant antibodies and affibodies in filamentous phages, Escherichia coli and other prokaryotic cells. Emphasis has been placed on improving phage and phagemid vectors, alternative systems for expression in different cellular compartments (e.g. the outer membrane, periplasm, cytoplasm and extracellular secretion) and novel multimerization systems for generating bivalent or multivalent binding molecules. |
| format | Online Article Text |
| id | pubmed-7172615 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2004 |
| publisher | Elsevier Ltd. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-71726152020-04-22 Prokaryotic expression of antibodies and affibodies Fernández, Luis Angel Curr Opin Biotechnol Article Recent advances have been made in the development of systems for the display and expression of recombinant antibodies and affibodies in filamentous phages, Escherichia coli and other prokaryotic cells. Emphasis has been placed on improving phage and phagemid vectors, alternative systems for expression in different cellular compartments (e.g. the outer membrane, periplasm, cytoplasm and extracellular secretion) and novel multimerization systems for generating bivalent or multivalent binding molecules. Elsevier Ltd. 2004-08 2004-06-22 /pmc/articles/PMC7172615/ /pubmed/15296932 http://dx.doi.org/10.1016/j.copbio.2004.06.004 Text en Copyright © 2004 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Article Fernández, Luis Angel Prokaryotic expression of antibodies and affibodies |
| title | Prokaryotic expression of antibodies and affibodies |
| title_full | Prokaryotic expression of antibodies and affibodies |
| title_fullStr | Prokaryotic expression of antibodies and affibodies |
| title_full_unstemmed | Prokaryotic expression of antibodies and affibodies |
| title_short | Prokaryotic expression of antibodies and affibodies |
| title_sort | prokaryotic expression of antibodies and affibodies |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172615/ https://www.ncbi.nlm.nih.gov/pubmed/15296932 http://dx.doi.org/10.1016/j.copbio.2004.06.004 |
| work_keys_str_mv | AT fernandezluisangel prokaryoticexpressionofantibodiesandaffibodies |