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Mutations within the nuclear localization signal of the porcine reproductive and respiratory syndrome virus nucleocapsid protein attenuate virus replication

Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus replicating in the cytoplasm, but the nucleocapsid (N) protein is specifically localized to the nucleus and nucleolus in virus-infected cells. A ‘pat7’ motif of 41-PGKK(N/S)KK has previously been identified in the N protein...

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Detalles Bibliográficos
Autores principales:	Lee, Changhee, Hodgins, Douglas, Calvert, Jay G., Welch, Siao-Kun W., Jolie, Rika, Yoo, Dongwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172752/ https://www.ncbi.nlm.nih.gov/pubmed/16330065 http://dx.doi.org/10.1016/j.virol.2005.11.005

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