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Localization of proteins to the Golgi apparatus

For the Golgi apparatus to perform its various unique roles it must maintain a population of resident proteins. These residents include the enzymes that modify the proteins and lipids passing through the Golgi, as well as the proteins involved in vesicle formation and protein sorting. For several of...

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Detalles Bibliográficos
Autor principal: Munro, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172754/
https://www.ncbi.nlm.nih.gov/pubmed/9695801
http://dx.doi.org/10.1016/S0962-8924(97)01197-5
Descripción
Sumario:For the Golgi apparatus to perform its various unique roles it must maintain a population of resident proteins. These residents include the enzymes that modify the proteins and lipids passing through the Golgi, as well as the proteins involved in vesicle formation and protein sorting. For several of these residents, it has been possible to identify regions that are crucial for specifying a Golgi localization. Consideration of how these targeting domains could function has provided insights into the organization of the Golgi and its protein and lipid content.