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Immunisation of pigs with a major envelope protein sub-unit vaccine against porcine reproductive and respiratory syndrome virus (PRRSV) results in enhanced clinical disease following experimental challenge

Disease exacerbation was observed in pigs challenged with virulent porcine reproductive and respiratory syndrome virus (PRRSV) following immunisation with a recombinant GP5 sub-unit PRRSV vaccine (rGP5) produced in E. coli. Eighteen animals were divided into three experimental groups: group A were i...

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Detalles Bibliográficos
Autores principales: Prieto, Cinta, Martínez-Lobo, Francisco Javier, Díez-Fuertes, Francisco, Aguilar-Calvo, Patricia, Simarro, Isabel, Castro, José María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172774/
https://www.ncbi.nlm.nih.gov/pubmed/20713312
http://dx.doi.org/10.1016/j.tvjl.2010.07.010