An insect cell derived respiratory syncytial virus (RSV) F nanoparticle vaccine induces antigenic site II antibodies and protects against RSV challenge in cotton rats by active and passive immunization

Post-infectious immunity to respiratory syncytial virus (RSV) infection results in limited protection as evidenced by the high rate of infant hospitalization in the face of high titer, maternally derived RSV-specific antibodies. By contrast, RSV fusion (F) glycoprotein antigenic site II humanized mo...

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Detalles Bibliográficos
Autores principales: Raghunandan, Rama, Lu, Hanxin, Zhou, Bin, Xabier, Mimi Guebre, Massare, Michael J., Flyer, David C., Fries, Louis F., Smith, Gale E., Glenn, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172787/
https://www.ncbi.nlm.nih.gov/pubmed/25269094
http://dx.doi.org/10.1016/j.vaccine.2014.09.030

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