Comparison of egg and high yielding MDCK cell-derived live attenuated influenza virus for commercial production of trivalent influenza vaccine: In vitro cell susceptibility and influenza virus replication kinetics in permissive and semi-permissive cells()

Currently MedImmune manufactures cold-adapted (ca) live, attenuated influenza vaccine (LAIV) from specific-pathogen free (SPF) chicken eggs. Difficulties in production scale-up and potential exposure of chicken flocks to avian influenza viruses especially in the event of a pandemic influenza outbrea...

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Detalles Bibliográficos
Autores principales: Hussain, Althaf I., Cordeiro, Melissa, Sevilla, Elizabeth, Liu, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172923/
https://www.ncbi.nlm.nih.gov/pubmed/20307595
http://dx.doi.org/10.1016/j.vaccine.2010.03.005

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