Cargando…

Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults

OBJECTIVES: Respiratory syncytial virus (RSV) causes respiratory infection across the world, with infants and the elderly at particular risk of developing severe disease and death. The replication-defective chimpanzee adenovirus (PanAd3-RSV) and modified vaccinia virus Ankara (MVA-RSV) vaccines were...

Descripción completa

Detalles Bibliográficos
Autores principales:	Green, Christopher A., Sande, Charles J., Scarselli, Elisa, Capone, Stefania, Vitelli, Alessandra, Nicosia, Alfredo, Silva-Reyes, Laura, Thompson, Amber J., de Lara, Catherine M., Taylor, Kathryn S., Haworth, Kathryn, Hutchings, Claire L., Cargill, Tamsin, Angus, Brian, Klenerman, Paul, Pollard, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Infection Association. Published by Elsevier Ltd. 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172982/ https://www.ncbi.nlm.nih.gov/pubmed/30742894 http://dx.doi.org/10.1016/j.jinf.2019.02.003

Ejemplares similares

Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-RSV); protocol for an open-label, dose-escalation, single-centre, phase 1 clinical trial in healthy adults
por: Green, C A, et al.
Publicado: (2015)

Transcriptomic response and immunological responses to chimpanzee adenovirus- and MVA viral-vectored vaccines for RSV in healthy adults
por: Green, C, et al.
Publicado: (2023)

Protective CD8(+) T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation
por: Ewer, Katie J., et al.
Publicado: (2013)

Evaluation of Chimpanzee Adenovirus and MVA Expressing TRAP and CSP from Plasmodium cynomolgi to Prevent Malaria Relapse in Nonhuman Primates
por: Kim, Young Chan, et al.
Publicado: (2020)

A novel Plasmodium vivax vaccine based on recombinant chimpanzee adenovirus ChAd63 and MVA expressing TRAP
por: Bauza, Karolis, et al.
Publicado: (2012)

A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C
por: Napolitano, Federico, et al.
Publicado: (2020)

Correction: A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C
por: Napolitano, Federico, et al.
Publicado: (2021)

The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV
por: Chinnakannan, Senthil K., et al.
Publicado: (2020)

First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector–Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults
por: Cicconi, Paola, et al.
Publicado: (2020)

Innate Immune Responses to Chimpanzee Adenovirus Vector 155 Vaccination in Mice and Monkeys
por: Collignon, Catherine, et al.
Publicado: (2020)

Influence of adenovirus and MVA vaccines on the breadth and hierarchy of T cell responses
por: Rollier, Christine S., et al.
Publicado: (2016)

Chimpanzee Adenovirus Antibodies in Humans, Sub-Saharan Africa
por: Xiang, Zhiquan, et al.
Publicado: (2006)

Combining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovirus-based COVID-19 vaccine elicits potent humoral and cellular immune responses in mice
por: Li, Xingxing, et al.
Publicado: (2022)

Short- and Long-Interval Prime-Boost Vaccination with the Candidate Vaccines MVA-SARS-2-ST and MVA-SARS-2-S Induces Comparable Humoral and Cell-Mediated Immunity in Mice
por: Kalodimou, Georgia, et al.
Publicado: (2023)

Lichenoid Drug Reaction Post-COVID Vaccination with the Modified Chimpanzee Adenovirus
por: García-Mendoza, Paola, et al.
Publicado: (2022)

Innate and secondary humoral responses are improved by increasing the time between MVA vaccine immunizations
por: Palgen, Jean-Louis, et al.
Publicado: (2020)

Immunity Against Heterosubtypic Influenza Virus Induced By Adenovirus And MVA Expressing Nucleoprotein And Matrix Protein-1
por: Lambe, Teresa, et al.
Publicado: (2013)

Humoral immunogenicity of ChAd63_MVA ME-TRAP vaccination in African infants and children
por: Bowyer, Georgina, et al.
Publicado: (2014)

Seroprevalence of Neutralizing Antibodies against Human Adenovirus Type-5 and Chimpanzee Adenovirus Type-68 in Cancer Patients
por: Zhao, Hua, et al.
Publicado: (2018)

The protective immunity induced by intranasally inoculated serotype 63 chimpanzee adenovirus vector expressing human respiratory syncytial virus prefusion fusion glycoprotein in BALB/c mice
por: Huang, Lei, et al.
Publicado: (2022)

Identification of Recombinant Chimpanzee Adenovirus C68 Degradation Products Detected by AEX-HPLC
por: Powers, Thomas W., et al.
Publicado: (2022)

Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-β1
por: Fletcher, Helen A., et al.
Publicado: (2008)

Immunogenicity and efficacy of a chimpanzee adenovirus-vectored Rift Valley Fever vaccine in mice
por: Warimwe, George M, et al.
Publicado: (2013)

Chimpanzee Adenovirus Vaccine Provides Multispecies Protection against Rift Valley Fever
por: Warimwe, George M., et al.
Publicado: (2016)

Potency of a thermostabilised chimpanzee adenovirus Rift Valley Fever vaccine in cattle
por: Dulal, Pawan, et al.
Publicado: (2016)

Chimpanzee adenovirus-mediated multiple gene therapy for age-related macular degeneration
por: Wei-Zhang, Selena, et al.
Publicado: (2023)

Mixed Vector Immunization With Recombinant Adenovirus and MVA Can Improve Vaccine Efficacy While Decreasing Antivector Immunity
por: Reyes-Sandoval, Arturo, et al.
Publicado: (2012)

Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SARS-CoV-2
por: Dicks, Matthew D.J., et al.
Publicado: (2022)

Analysis of T cell responses to chimpanzee adenovirus vectors encoding HIV gag–pol–nef antigen
por: Herath, S., et al.
Publicado: (2015)

Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques
por: Vierboom, Michel P. M., et al.
Publicado: (2020)

P19-58 LB. Comparison of the immunogenicity in humans and rhesus macaques of vaccines consisting of DNA priming and MVA boosting and MVA priming and boosting
por: Robinson, HL, et al.
Publicado: (2009)

Safety and Immunogenicity of Boosting BCG Vaccinated Subjects with BCG: Comparison with Boosting with a New TB Vaccine, MVA85A
por: Whelan, Kathryn T., et al.
Publicado: (2009)

Assessment of Humoral Immune Responses to Blood-Stage Malaria Antigens following ChAd63-MVA Immunization, Controlled Human Malaria Infection and Natural Exposure
por: Biswas, Sumi, et al.
Publicado: (2014)

Correction: Safety and Immunogenicity of Boosting BCG Vaccinated Subjects with BCG: Comparison with Boosting with a New TB Vaccine, MVA85A
por: Whelan, Kathryn T., et al.
Publicado: (2011)

Potent cellular and humoral immunity against HIV-1 elicited in mice by a DNA-prime/MVA-boost vaccine regimen intended for human use
por: Wahren, Britta, et al.
Publicado: (2006)

A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity
por: Dicks, Matthew D. J., et al.
Publicado: (2012)

Adenovirus Encoded Adjuvant (AdEnA) anti-CTLA-4, a novel strategy to improve Adenovirus based vaccines against infectious diseases and cancer
por: D’Alise, Anna Morena, et al.
Publicado: (2023)

A Scan for Positively Selected Genes in the Genomes of Humans and Chimpanzees
por: Nielsen, Rasmus, et al.
Publicado: (2005)

Reduced Respiratory Syncytial Virus Load, Symptoms, and Infections: A Human Challenge Trial of MVA-BN-RSV Vaccine
por: Jordan, Elke, et al.
Publicado: (2023)

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers
por: Capucci, Silvia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vpst20aamb9g28clhb5emarruu