The α(1,2)‐mannosidase I inhibitor 1‐deoxymannojirimycin potentiates the antiviral activity of carbohydrate‐binding agents against wild‐type and mutant HIV‐1 strains containing glycan deletions in gp120

Exposure of carbohydrate‐binding agents (CBAs) (i.e. the mannose‐specific plant lectins Hippeastrum hybrid agglutinin and Galanthus nivalis agglutinin) to HIV‐1 progressively select for mutant HIV‐1 strains that contain N‐glycan deletions in their envelope gp120. This results in resistance of the mu...

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Detalles Bibliográficos
Autor principal: Balzarini, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2007
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173009/
https://www.ncbi.nlm.nih.gov/pubmed/17475258
http://dx.doi.org/10.1016/j.febslet.2007.04.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173009/
https://www.ncbi.nlm.nih.gov/pubmed/17475258
http://dx.doi.org/10.1016/j.febslet.2007.04.039

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