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Agonist and antagonist ligands of toll-like receptors 7 and 8: Ingenious tools for therapeutic purposes
The discovery of the TLRs family and more precisely its functions opened a variety of gates to modulate immunological host responses. TLRs 7/8 are located in the endosomal compartment and activate a specific signaling pathway in a MyD88-dependant manner. According to their involvement into various a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Masson SAS.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173040/ https://www.ncbi.nlm.nih.gov/pubmed/32203790 http://dx.doi.org/10.1016/j.ejmech.2020.112238 |