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The origin of HIV-1, the AIDS virus
This article proposes a series of experiments to determine if cows and sheep could be used as animal models for HIV-1, the AIDS virus. To justify this effort, a substantial case is presented that HIV-1 is a natural recombinant of Bovine Leukemia Virus (BLV) and Visna Virus. This natural recombinant...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Published by Elsevier Ltd.
1993
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173098/ https://www.ncbi.nlm.nih.gov/pubmed/8289690 http://dx.doi.org/10.1016/0306-9877(93)90069-3 |
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author | Siefkes, D. |
author_facet | Siefkes, D. |
author_sort | Siefkes, D. |
collection | PubMed |
description | This article proposes a series of experiments to determine if cows and sheep could be used as animal models for HIV-1, the AIDS virus. To justify this effort, a substantial case is presented that HIV-1 is a natural recombinant of Bovine Leukemia Virus (BLV) and Visna Virus. This natural recombinant may have been inadvertently transferred to humans through the Intensified Smallpox Eradication Program conducted in sub-Saharan Africa in the late 1960s and most of the 1970s. |
format | Online Article Text |
id | pubmed-7173098 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1993 |
publisher | Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71730982020-04-22 The origin of HIV-1, the AIDS virus Siefkes, D. Med Hypotheses Article This article proposes a series of experiments to determine if cows and sheep could be used as animal models for HIV-1, the AIDS virus. To justify this effort, a substantial case is presented that HIV-1 is a natural recombinant of Bovine Leukemia Virus (BLV) and Visna Virus. This natural recombinant may have been inadvertently transferred to humans through the Intensified Smallpox Eradication Program conducted in sub-Saharan Africa in the late 1960s and most of the 1970s. Published by Elsevier Ltd. 1993-10 2004-03-22 /pmc/articles/PMC7173098/ /pubmed/8289690 http://dx.doi.org/10.1016/0306-9877(93)90069-3 Text en Copyright © 1993 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Siefkes, D. The origin of HIV-1, the AIDS virus |
title | The origin of HIV-1, the AIDS virus |
title_full | The origin of HIV-1, the AIDS virus |
title_fullStr | The origin of HIV-1, the AIDS virus |
title_full_unstemmed | The origin of HIV-1, the AIDS virus |
title_short | The origin of HIV-1, the AIDS virus |
title_sort | origin of hiv-1, the aids virus |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173098/ https://www.ncbi.nlm.nih.gov/pubmed/8289690 http://dx.doi.org/10.1016/0306-9877(93)90069-3 |
work_keys_str_mv | AT siefkesd theoriginofhiv1theaidsvirus AT siefkesd originofhiv1theaidsvirus |