The potential use of liposome-mediated antiviral therapy

The natural targeting of liposomes to cells of the reticuloendothelial system should be exploited to examine whether selective delivery of antiviral or immunomodulatory agents could be beneficial for the treatment of viral diseases. In this review we discuss the potential use of liposomes in the tre...

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Detalles Bibliográficos
Autores principales: Koff, Wayne C., Fidler, Isaiah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1985
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173127/
https://www.ncbi.nlm.nih.gov/pubmed/3896138
http://dx.doi.org/10.1016/0166-3542(85)90050-6
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author Koff, Wayne C.
Fidler, Isaiah J.
author_facet Koff, Wayne C.
Fidler, Isaiah J.
author_sort Koff, Wayne C.
collection PubMed
description The natural targeting of liposomes to cells of the reticuloendothelial system should be exploited to examine whether selective delivery of antiviral or immunomodulatory agents could be beneficial for the treatment of viral diseases. In this review we discuss the potential use of liposomes in the treatment of virus diseases, the targeting of liposome-encapsulated immunomodulators to macrophages in order to render these cells cytolytic for virus-infected cells, and the targeting of liposome-encapsulated antiviral drugs to macrophages to achieve direct suppression of virus replication within these cells.
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spelling pubmed-71731272020-04-22 The potential use of liposome-mediated antiviral therapy Koff, Wayne C. Fidler, Isaiah J. Antiviral Res Article The natural targeting of liposomes to cells of the reticuloendothelial system should be exploited to examine whether selective delivery of antiviral or immunomodulatory agents could be beneficial for the treatment of viral diseases. In this review we discuss the potential use of liposomes in the treatment of virus diseases, the targeting of liposome-encapsulated immunomodulators to macrophages in order to render these cells cytolytic for virus-infected cells, and the targeting of liposome-encapsulated antiviral drugs to macrophages to achieve direct suppression of virus replication within these cells. Published by Elsevier B.V. 1985-06 2002-11-12 /pmc/articles/PMC7173127/ /pubmed/3896138 http://dx.doi.org/10.1016/0166-3542(85)90050-6 Text en Copyright © 1985 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Koff, Wayne C.
Fidler, Isaiah J.
The potential use of liposome-mediated antiviral therapy
title The potential use of liposome-mediated antiviral therapy
title_full The potential use of liposome-mediated antiviral therapy
title_fullStr The potential use of liposome-mediated antiviral therapy
title_full_unstemmed The potential use of liposome-mediated antiviral therapy
title_short The potential use of liposome-mediated antiviral therapy
title_sort potential use of liposome-mediated antiviral therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173127/
https://www.ncbi.nlm.nih.gov/pubmed/3896138
http://dx.doi.org/10.1016/0166-3542(85)90050-6
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