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Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid
The series of 16 novel amino acid and peptide mycophenolic acid (MPA) derivatives was obtained as potential antibacterial agents. Coupling of MPA with respective amines was optimized with condensing reagents such as EDCI/DMAP and T3P/TEA. Amino acid analogs were received both as methyl esters and al...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Masson SAS.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173178/ https://www.ncbi.nlm.nih.gov/pubmed/29216563 http://dx.doi.org/10.1016/j.ejmech.2017.11.094 |