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Recent trends in click chemistry as a promising technology for virus-related research
Click chemistry involves reactions that were originally introduced and used in organic chemistry to generate substances by joining small units together with heteroatom linkages (C-X-C). Over the last few decades, click chemistry has been widely used in virus-related research. Using click chemistry,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173221/ https://www.ncbi.nlm.nih.gov/pubmed/30081058 http://dx.doi.org/10.1016/j.virusres.2018.08.003 |
_version_ | 1783524410050740224 |
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author | Ouyang, Ting Liu, Xiaohui Ouyang, Hongsheng Ren, Linzhu |
author_facet | Ouyang, Ting Liu, Xiaohui Ouyang, Hongsheng Ren, Linzhu |
author_sort | Ouyang, Ting |
collection | PubMed |
description | Click chemistry involves reactions that were originally introduced and used in organic chemistry to generate substances by joining small units together with heteroatom linkages (C-X-C). Over the last few decades, click chemistry has been widely used in virus-related research. Using click chemistry, the virus particle as well as viral protein and nucleic acids can be labeled. Subsequently, the labeled virions or molecules can be tracked in real time. Here, we reviewed the recent applications of click reactions in virus-related research, including viral tracking, the design of antiviral agents, the diagnosis of viral infection, and virus-based delivery systems. This review provides an overview of the general principles and applications of click chemistry in virus-related research. |
format | Online Article Text |
id | pubmed-7173221 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71732212020-04-22 Recent trends in click chemistry as a promising technology for virus-related research Ouyang, Ting Liu, Xiaohui Ouyang, Hongsheng Ren, Linzhu Virus Res Review Click chemistry involves reactions that were originally introduced and used in organic chemistry to generate substances by joining small units together with heteroatom linkages (C-X-C). Over the last few decades, click chemistry has been widely used in virus-related research. Using click chemistry, the virus particle as well as viral protein and nucleic acids can be labeled. Subsequently, the labeled virions or molecules can be tracked in real time. Here, we reviewed the recent applications of click reactions in virus-related research, including viral tracking, the design of antiviral agents, the diagnosis of viral infection, and virus-based delivery systems. This review provides an overview of the general principles and applications of click chemistry in virus-related research. Elsevier B.V. 2018-09-02 2018-08-03 /pmc/articles/PMC7173221/ /pubmed/30081058 http://dx.doi.org/10.1016/j.virusres.2018.08.003 Text en © 2018 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Ouyang, Ting Liu, Xiaohui Ouyang, Hongsheng Ren, Linzhu Recent trends in click chemistry as a promising technology for virus-related research |
title | Recent trends in click chemistry as a promising technology for virus-related research |
title_full | Recent trends in click chemistry as a promising technology for virus-related research |
title_fullStr | Recent trends in click chemistry as a promising technology for virus-related research |
title_full_unstemmed | Recent trends in click chemistry as a promising technology for virus-related research |
title_short | Recent trends in click chemistry as a promising technology for virus-related research |
title_sort | recent trends in click chemistry as a promising technology for virus-related research |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173221/ https://www.ncbi.nlm.nih.gov/pubmed/30081058 http://dx.doi.org/10.1016/j.virusres.2018.08.003 |
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