Bacterial Interference of Ubiquitination and Deubiquitination

Ubiquitination and deubiquitination regulate several essential cellular processes such as protein degradation, cell-cycle progression, signaling, and DNA repair. Given the importance of these processes, it is not surprising that many microbes have developed the means to interfere with different stag...

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Detalles Bibliográficos
Autores principales: Rytkönen, Anne, Holden, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173291/
https://www.ncbi.nlm.nih.gov/pubmed/18005678
http://dx.doi.org/10.1016/j.chom.2007.02.003
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author Rytkönen, Anne
Holden, David W.
author_facet Rytkönen, Anne
Holden, David W.
author_sort Rytkönen, Anne
collection PubMed
description Ubiquitination and deubiquitination regulate several essential cellular processes such as protein degradation, cell-cycle progression, signaling, and DNA repair. Given the importance of these processes, it is not surprising that many microbes have developed the means to interfere with different stages of ubiquitin pathways to promote their survival and replication. This review focuses on virulence proteins of bacterial pathogens that mediate these effects and summarizes our current understanding of their actions.
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spelling pubmed-71732912020-04-22 Bacterial Interference of Ubiquitination and Deubiquitination Rytkönen, Anne Holden, David W. Cell Host Microbe Review Ubiquitination and deubiquitination regulate several essential cellular processes such as protein degradation, cell-cycle progression, signaling, and DNA repair. Given the importance of these processes, it is not surprising that many microbes have developed the means to interfere with different stages of ubiquitin pathways to promote their survival and replication. This review focuses on virulence proteins of bacterial pathogens that mediate these effects and summarizes our current understanding of their actions. Elsevier Inc. 2007-03-15 2007-03-13 /pmc/articles/PMC7173291/ /pubmed/18005678 http://dx.doi.org/10.1016/j.chom.2007.02.003 Text en Copyright © 2007 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Rytkönen, Anne
Holden, David W.
Bacterial Interference of Ubiquitination and Deubiquitination
title Bacterial Interference of Ubiquitination and Deubiquitination
title_full Bacterial Interference of Ubiquitination and Deubiquitination
title_fullStr Bacterial Interference of Ubiquitination and Deubiquitination
title_full_unstemmed Bacterial Interference of Ubiquitination and Deubiquitination
title_short Bacterial Interference of Ubiquitination and Deubiquitination
title_sort bacterial interference of ubiquitination and deubiquitination
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173291/
https://www.ncbi.nlm.nih.gov/pubmed/18005678
http://dx.doi.org/10.1016/j.chom.2007.02.003
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