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Inactivation of viral antigens for vaccine preparation with particular reference to the application of binary ethylenimine
Viral antigens for human and veterinary vaccines are still inactivated with formaldehyde. This is not an ideal inactivant and the problems of formaldehyde inactivation of vaccines are discussed. Vaccines inactivated with aziridines are superior in safety and antigenicity. Aziridines inactivate virus...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Published by Elsevier Ltd.
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173316/ https://www.ncbi.nlm.nih.gov/pubmed/2204242 http://dx.doi.org/10.1016/0264-410X(90)90083-X |