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RNA chaperone activity of the tombusviral p33 replication protein facilitates initiation of RNA synthesis by the viral RdRp in vitro

Small plus-stranded RNA viruses do not code for RNA helicases that would facilitate the proper folding of viral RNAs during replication. Instead, these viruses might use RNA chaperones as shown here for the essential p33 replication protein of Tomato bushy stunt virus (TBSV). In vitro experiments de...

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Detalles Bibliográficos
Autores principales: Stork, Jozsef, Kovalev, Nikolay, Sasvari, Zsuzsanna, Nagy, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173327/
https://www.ncbi.nlm.nih.gov/pubmed/21071052
http://dx.doi.org/10.1016/j.virol.2010.10.015