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Longer Hydroxyurea Administration Prior to Imatinib Mesylate is Risk Factor for Unsuccessful Major Molecular Response in Chronic-Phase Chronic Myeloid Leukemia: Possibility of P-Glycoprotein Role

OBJECTIVE: This study aimed to identify the association between duration of HU administration prior to IM treatment and MMR achievement in chronic-phase CML while evaluating the role of MDA, HIF-1α and P-gp. METHODS: The study was conducted at Dr. Cipto Mangunkusumo National General Hospital and Dha...

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Detalles Bibliográficos
Autores principales: Rinaldi, Ikhwan, Reksodiputro, Ary Harryanto, Jusman, Sri Widia, Harahap, Alida, Setiabudy, Rianto, Wanandi, Septelia Inawati, Tambunan, Karmel, Suharti, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173389/
https://www.ncbi.nlm.nih.gov/pubmed/31870110
http://dx.doi.org/10.31557/APJCP.2019.20.12.3689

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