Role of BIM Deletion Polymorphism and BIM Expression as Predictive Biomarkers to Maximize the Benefit of EGFR-TKI Treatment in EGFR-Positive NSCLC

OBJECTIVE: BIM is a modulator of apoptosis that is triggered by EGFR-TKIs. This study evaluated the role of BIM deletion and its expression as predictor of EGFR-TKI treatment outcome. METHODS: The medical record of 185 EGFR-positive advanced non-small cell lung cancer (NSCLC) patients with/ without...

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Detalles Bibliográficos
Autores principales: Incharoen, Pimpin, Charonpongsuntorn, Chanchai, Saowapa, Sakditad, Sirachainan, Ekaphop, Dejthevaporn, Thitiya, Kampreasart, Kaettipong, Trachu, Narumol, Muntham, Dittapol, Reungwetwattana, Thanyanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173394/
https://www.ncbi.nlm.nih.gov/pubmed/31870097
http://dx.doi.org/10.31557/APJCP.2019.20.12.3581

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