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Nature and Pathogenicity of Micro-organisms
• Micro-organisms and higher organisms have evolved together and interact in complex ways. Only a small percentage of microbes are inherently pathogenic. • Pathogenicity, the ability of infectious agents to cause disease, must be interpreted in the context of the properties of both transmissible age...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173513/ http://dx.doi.org/10.1016/B978-0-7020-6285-8.00002-2 |
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author | Fierer, Joshua Looney, David Pechère, Jean-Claude |
author_facet | Fierer, Joshua Looney, David Pechère, Jean-Claude |
author_sort | Fierer, Joshua |
collection | PubMed |
description | • Micro-organisms and higher organisms have evolved together and interact in complex ways. Only a small percentage of microbes are inherently pathogenic. • Pathogenicity, the ability of infectious agents to cause disease, must be interpreted in the context of the properties of both transmissible agent and host. • Understanding this interplay is important to developing methods to prevent infection and reduce the severity of disease. • The initial step in infection is usually adherence, mediated by the interaction of surface structures on the pathogen with host cell membrane proteins or carbohydrates. This often presents excellent targets for immunity. • Intracellular pathogens have evolved methods to neutralize the cellular defenses that can destroy invaders. |
format | Online Article Text |
id | pubmed-7173513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
record_format | MEDLINE/PubMed |
spelling | pubmed-71735132020-04-22 Nature and Pathogenicity of Micro-organisms Fierer, Joshua Looney, David Pechère, Jean-Claude Infectious Diseases Article • Micro-organisms and higher organisms have evolved together and interact in complex ways. Only a small percentage of microbes are inherently pathogenic. • Pathogenicity, the ability of infectious agents to cause disease, must be interpreted in the context of the properties of both transmissible agent and host. • Understanding this interplay is important to developing methods to prevent infection and reduce the severity of disease. • The initial step in infection is usually adherence, mediated by the interaction of surface structures on the pathogen with host cell membrane proteins or carbohydrates. This often presents excellent targets for immunity. • Intracellular pathogens have evolved methods to neutralize the cellular defenses that can destroy invaders. 2017 2016-08-12 /pmc/articles/PMC7173513/ http://dx.doi.org/10.1016/B978-0-7020-6285-8.00002-2 Text en Copyright © 2017 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Fierer, Joshua Looney, David Pechère, Jean-Claude Nature and Pathogenicity of Micro-organisms |
title | Nature and Pathogenicity of Micro-organisms |
title_full | Nature and Pathogenicity of Micro-organisms |
title_fullStr | Nature and Pathogenicity of Micro-organisms |
title_full_unstemmed | Nature and Pathogenicity of Micro-organisms |
title_short | Nature and Pathogenicity of Micro-organisms |
title_sort | nature and pathogenicity of micro-organisms |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173513/ http://dx.doi.org/10.1016/B978-0-7020-6285-8.00002-2 |
work_keys_str_mv | AT fiererjoshua natureandpathogenicityofmicroorganisms AT looneydavid natureandpathogenicityofmicroorganisms AT pecherejeanclaude natureandpathogenicityofmicroorganisms |