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Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010

We aimed to investigate the association of various obesity parameters and phenotypes with hypertension in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2008–2010, a total of 16,363 subje...

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Autores principales: Seok Lee, Hong, Park, Yong-Moon, Han, Kyungdo, Yang, Jin-Hong, Lee, Seungwon, Lee, Seong‐Su, Yoo, Soonjib, Kim, Sung Rae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173931/
https://www.ncbi.nlm.nih.gov/pubmed/32315310
http://dx.doi.org/10.1371/journal.pone.0230616
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author Seok Lee, Hong
Park, Yong-Moon
Han, Kyungdo
Yang, Jin-Hong
Lee, Seungwon
Lee, Seong‐Su
Yoo, Soonjib
Kim, Sung Rae
author_facet Seok Lee, Hong
Park, Yong-Moon
Han, Kyungdo
Yang, Jin-Hong
Lee, Seungwon
Lee, Seong‐Su
Yoo, Soonjib
Kim, Sung Rae
author_sort Seok Lee, Hong
collection PubMed
description We aimed to investigate the association of various obesity parameters and phenotypes with hypertension in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2008–2010, a total of 16,363 subjects (8,184 men and 8,179 women) were analyzed. Hypertension was defined as blood pressure of 140/90 mm Hg or higher or taking antihypertensive medication. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Higher obesity parameters [body mass index (BMI) representing general obesity, waist circumference (WC) representing central obesity, and percentage body fat (PBF) representing elevated body fat] were consistently associated with increased odds of prevalent hypertension (OR, 7.54; 95% CI, 5.89–9.65 for BMI ≥30 vs. 18.5–23; OR, 3.97; 95% CI, 3.41–4.63 for WC ≥95 cm in males and ≥90 cm in females vs. <85 cm in males and <80 cm in females; OR, 3.56; 95% CI, 3.05–4.15 for PBF, highest vs. lowest quartile; all p trends<0.0001). These associations were stronger in the younger age group (<40 years), and were observed in both sexes. Furthermore, even in individuals with normal BMI (18.5–23), the odds of prevalent hypertension were consistently increased in those with central obesity (WC≥90 cm in males, WC≥80 cm in females; normal weight central obesity phenotype) (OR, 1.89; 95% CI, 1.63–2.19) and those with high PBF (highest quartile of PBF; normal weight obesity phenotype) (OR, 1.49; 95% CI, 1.25–1.77). These associations were consistent with updated hypertension guidelines in 2017. Obesity may be positively associated with hypertension, regardless of obesity parameters. Even within normal BMI range, high WC and high PBF may be associated with hypertension.
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spelling pubmed-71739312020-04-27 Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010 Seok Lee, Hong Park, Yong-Moon Han, Kyungdo Yang, Jin-Hong Lee, Seungwon Lee, Seong‐Su Yoo, Soonjib Kim, Sung Rae PLoS One Research Article We aimed to investigate the association of various obesity parameters and phenotypes with hypertension in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2008–2010, a total of 16,363 subjects (8,184 men and 8,179 women) were analyzed. Hypertension was defined as blood pressure of 140/90 mm Hg or higher or taking antihypertensive medication. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Higher obesity parameters [body mass index (BMI) representing general obesity, waist circumference (WC) representing central obesity, and percentage body fat (PBF) representing elevated body fat] were consistently associated with increased odds of prevalent hypertension (OR, 7.54; 95% CI, 5.89–9.65 for BMI ≥30 vs. 18.5–23; OR, 3.97; 95% CI, 3.41–4.63 for WC ≥95 cm in males and ≥90 cm in females vs. <85 cm in males and <80 cm in females; OR, 3.56; 95% CI, 3.05–4.15 for PBF, highest vs. lowest quartile; all p trends<0.0001). These associations were stronger in the younger age group (<40 years), and were observed in both sexes. Furthermore, even in individuals with normal BMI (18.5–23), the odds of prevalent hypertension were consistently increased in those with central obesity (WC≥90 cm in males, WC≥80 cm in females; normal weight central obesity phenotype) (OR, 1.89; 95% CI, 1.63–2.19) and those with high PBF (highest quartile of PBF; normal weight obesity phenotype) (OR, 1.49; 95% CI, 1.25–1.77). These associations were consistent with updated hypertension guidelines in 2017. Obesity may be positively associated with hypertension, regardless of obesity parameters. Even within normal BMI range, high WC and high PBF may be associated with hypertension. Public Library of Science 2020-04-21 /pmc/articles/PMC7173931/ /pubmed/32315310 http://dx.doi.org/10.1371/journal.pone.0230616 Text en © 2020 Seok Lee et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Seok Lee, Hong
Park, Yong-Moon
Han, Kyungdo
Yang, Jin-Hong
Lee, Seungwon
Lee, Seong‐Su
Yoo, Soonjib
Kim, Sung Rae
Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010
title Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010
title_full Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010
title_fullStr Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010
title_full_unstemmed Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010
title_short Obesity-related hypertension: Findings from The Korea National Health and Nutrition Examination Survey 2008–2010
title_sort obesity-related hypertension: findings from the korea national health and nutrition examination survey 2008–2010
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173931/
https://www.ncbi.nlm.nih.gov/pubmed/32315310
http://dx.doi.org/10.1371/journal.pone.0230616
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