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Molecular mechanism for bidirectional regulation of CD44 for lipid raft affiliation by palmitoylations and PIP2

The co-localization of Cluster-of-Differentiation-44 protein (CD44) and cytoplasmic adaptors in specific membrane environments is crucial for cell adhesion and migration. The process is controlled by two different pathways: On the one hand palmitoylation keeps CD44 in lipid raft domains and disables...

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Detalles Bibliográficos
Autores principales: Sun, Fude, Schroer, Carsten F. E., Palacios, Carlos R., Xu, Lida, Luo, Shi-Zhong, Marrink, Siewert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173942/
https://www.ncbi.nlm.nih.gov/pubmed/32271757
http://dx.doi.org/10.1371/journal.pcbi.1007777

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