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Molecular mechanism for bidirectional regulation of CD44 for lipid raft affiliation by palmitoylations and PIP2
The co-localization of Cluster-of-Differentiation-44 protein (CD44) and cytoplasmic adaptors in specific membrane environments is crucial for cell adhesion and migration. The process is controlled by two different pathways: On the one hand palmitoylation keeps CD44 in lipid raft domains and disables...
Autores principales: | Sun, Fude, Schroer, Carsten F. E., Palacios, Carlos R., Xu, Lida, Luo, Shi-Zhong, Marrink, Siewert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173942/ https://www.ncbi.nlm.nih.gov/pubmed/32271757 http://dx.doi.org/10.1371/journal.pcbi.1007777 |
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