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Cell death induced by cytotoxic CD8(+) T cells is immunogenic and primes caspase-3–dependent spread immunity against endogenous tumor antigens

BACKGROUND: Elimination of cancer cells by some stimuli like chemotherapy and radiotherapy activates anticancer immunity after the generation of damage‐associated molecular patterns, a process recently named immunogenic cell death (ICD). Despite the recent advances in cancer immunotherapy, very litt...

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Detalles Bibliográficos
Autores principales: Jaime-Sanchez, Paula, Uranga-Murillo, Iratxe, Aguilo, Nacho, Khouili, Sofia C, Arias, Maykel A, Sancho, David, Pardo, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174069/
https://www.ncbi.nlm.nih.gov/pubmed/32241808
http://dx.doi.org/10.1136/jitc-2020-000528