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T cell receptor repertoire characteristics both before and following immunotherapy correlate with clinical response in mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is a highly lethal malignancy in need for new treatment options. Although immunotherapies have been shown to boost a tumor-specific immune response, not all patients respond and prognostic biomarkers are scarce. In this study, we determined the periph...

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Detalles Bibliográficos
Autores principales:	Vroman, Heleen, Balzaretti, Giulia, Belderbos, Robert A, Klarenbeek, Paul L, van Nimwegen, Menno, Bezemer, Koen, Cornelissen, Robin, Niewold, Ilse T G, van Schaik, Barbera D, van Kampen, Antione H, Aerts, Joachim G J V, de Vries, Niek, Hendriks, Rudi W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174074/ https://www.ncbi.nlm.nih.gov/pubmed/32234848 http://dx.doi.org/10.1136/jitc-2019-000251

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