Cargando…

Dietary flavonoid myricetin inhibits invasion and migration of radioresistant lung cancer cells (A549‐IR) by suppressing MMP‐2 and MMP‐9 expressions through inhibition of the FAK‐ERK signaling pathway

Myricetin is a commonly found dietary flavonoid. In the present study, we investigated the effects of myricetin on migration and invasion of radioresistant lung cancer cells (A549‐IR). Transcriptome analysis of A549‐IR cells identified several differentially expressed genes (DEGs) in A549‐IR cells c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Hye R., Moon, Jeong Y., Ediriweera, Meran K., Song, Yeon W., Cho, Moonjae, Kasiviswanathan, Dharanibalan, Cho, Somi K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174229/ https://www.ncbi.nlm.nih.gov/pubmed/32328272 http://dx.doi.org/10.1002/fsn3.1495

Ejemplares similares

Inhibition of MMP1, MMP2 and MMP8 by mepacrine
por: Pollaschek, C, et al.
Publicado: (2003)

Inhibition of a Snake Venom Metalloproteinase by the Flavonoid Myricetin
por: Preciado, Lina María, et al.
Publicado: (2018)

Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin
por: Nguyen, Yen Thi-Kim, et al.
Publicado: (2020)

Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2
por: Sáenz-de-Santa-María, Inés, et al.
Publicado: (2020)

Isothiocyanates suppress the invasion and metastasis of tumors by targeting FAK/MMP-9 activity
por: Jeong, Yun-Jeong, et al.
Publicado: (2017)

Interplay between Phytochemicals and the Colonic Microbiota
por: Kwon, Chohee, et al.
Publicado: (2023)

Total Flavonoids of Scutellaria barbata Inhibit Invasion of Hepatocarcinoma via MMP/TIMP in Vitro
por: Dai, Zhi-Jun, et al.
Publicado: (2013)

Inhibition of MMP-2 and MMP-9 Activities by Limonium tetragonum Extract
por: Bae, Min-Joo, et al.
Publicado: (2016)

MMP-11 promoted the oral cancer migration and FAK/Src activation
por: Hsin, Chung-Han, et al.
Publicado: (2017)

The Role of MMP-9 and MMP-9 Inhibition in Different Types of Thyroid Carcinoma
por: Li, Zhenshengnan, et al.
Publicado: (2023)

The Protective Effects of Flavonoids in Cataract Formation through the Activation of Nrf2 and the Inhibition of MMP-9
por: Hilliard, Aaron, et al.
Publicado: (2020)

Sevoflurane Inhibits Metastasis in Hepatocellular Carcinoma by Inhibiting MiR-665-Induced Activation of the ERK/MMP Pathway
por: Zhu, Xiaoyan, et al.
Publicado: (2022)

LOX inhibition downregulates MMP-2 and MMP-9 in gastric cancer tissues and cells
por: Zhao, Lei, et al.
Publicado: (2019)

TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways
por: Wang, Yuhui, et al.
Publicado: (2017)

By inhibiting Ras/Raf/ERK and MMP-9, knockdown of EpCAM inhibits breast cancer cell growth and metastasis
por: Gao, Jiujiao, et al.
Publicado: (2015)

Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma
por: Webb, Anderson H., et al.
Publicado: (2017)

Effects of Combined Pentadecanoic Acid and Tamoxifen Treatment on Tamoxifen Resistance in MCF−7/SC Breast Cancer Cells
por: To, Ngoc Bao, et al.
Publicado: (2022)

Lipoxin A(4) Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer
por: Zong, Liang, et al.
Publicado: (2016)

Antcin-H Isolated from Antrodia cinnamomea Inhibits Renal Cancer Cell Invasion Partly through Inactivation of FAK-ERK-C/EBP-β/c-Fos-MMP-7 Pathways
por: Chiu, Kun-Yuan, et al.
Publicado: (2017)

Cinnamomum Cassia Extracts Suppress Human Lung Cancer Cells Invasion by Reducing u-PA/MMP Expression through the FAK to ERK Pathways
por: Wu, Hsing-Chen, et al.
Publicado: (2018)

Finasteride Inhibits Human Prostate Cancer Cell Invasion through MMP2 and MMP9 Downregulation
por: Moroz, Andrei, et al.
Publicado: (2013)

Diosmetin inhibits the metastasis of hepatocellular carcinoma cells by downregulating the expression levels of MMP-2 and MMP-9
por: LIU, JIE, et al.
Publicado: (2016)

Inhibition of Neutrophil Collagenase/MMP-8 and Gelatinase B/MMP-9 and Protection against Endotoxin Shock
por: Qiu, Zheng, et al.
Publicado: (2014)

Lupinus albus Protein Components Inhibit MMP-2 and MMP-9 Gelatinolytic Activity In Vitro and In Vivo
por: Mota, Joana, et al.
Publicado: (2021)

Quercetin Inhibits the Migration and Invasion of HCCLM3 Cells by Suppressing the Expression of p-Akt1, Matrix Metalloproteinase (MMP) MMP-2, and MMP-9
por: Lu, Jun, et al.
Publicado: (2018)

10-Gingerol Targets Lipid Rafts Associated PI3K/Akt Signaling in Radio-Resistant Triple Negative Breast Cancer Cells
por: Ediriweera, Meran Keshawa, et al.
Publicado: (2020)

Heparan Sulfate Proteoglycans Mediate Interstitial Flow Mechanotransduction Regulating MMP-13 Expression and Cell Motility via FAK-ERK in 3D Collagen
por: Shi, Zhong-Dong, et al.
Publicado: (2011)

Cdc42 Inhibits ERK-mediated Collagenase-1 (MMP-1) Expression in Collagen-Activated Human Keratinocytes
por: Rohani, Maryam G., et al.
Publicado: (2013)

Cordycepin attenuates migration and invasion of HSC-4 oral squamous carcinoma cells through autophagy-dependent FAK/Akt and MMP2/MMP9 suppression
por: Binlateh, Thunwa, et al.
Publicado: (2022)

MMP-1, MMP-3 and MMP-10 are involved in the degradation of cartilage
por: Tolboom, TCA, et al.
Publicado: (2001)

Combinatorial engineering of N-TIMP2 variants that selectively inhibit MMP9 and MMP14 function in the cell
por: Arkadash, Valeria, et al.
Publicado: (2018)

Molecular Mechanisms of MmpL3 Function and Inhibition
por: Williams, John T., et al.
Publicado: (2023)

Electrostatic Interactions Enable Nanoparticle Delivery of the Flavonoid Myricetin
por: Sims, Kenneth R., et al.
Publicado: (2020)

Early and Late Changes of MMP-2 and MMP-9 in Bleomycin-Induced Pulmonary Fibrosis
por: Kim, Ji Young, et al.
Publicado: (2009)

Antioxidant activity of banana flesh and antiproliferative effect on breast and pancreatic cancer cells
por: Kim, Dae Kyeong, et al.
Publicado: (2022)

Growth-stimulatory activity of TIMP-2 is mediated through c-Src activation followed by activation of FAK, PI3-kinase/AKT, and ERK1/2 independent of MMP inhibition in lung adenocarcinoma cells
por: Kim, Han Ie, et al.
Publicado: (2015)

ELK3 Suppresses Angiogenesis by Inhibiting the Transcriptional Activity of ETS-1 on MT1-MMP
por: Heo, Sun-Hee, et al.
Publicado: (2014)

Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas
por: Meneses-García, Abelardo, et al.
Publicado: (2008)

Genetic Association of MMP10, MMP14, and MMP16 with Dental Caries
por: Lewis, D. D., et al.
Publicado: (2017)

Modulation of RECK levels in Xenopus A6 cells: effects on MT1-MMP, MMP-2 and pERK levels
por: Willson, Jessica A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_sbpe54nkr64g7fo5rgqfgikjk4