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Exploring phase contrast imaging with a laser-based K(α) x-ray source up to relativistic laser intensity
This study explores the ability of a hard K(α) x-ray source (17.48 keV) produced by a 10 TW class laser system operated at high temporal contrast ratio and high repetition rate for phase contrast imaging. For demonstration, a parametric study based on a known object (PET films) shows clear evidence...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174335/ https://www.ncbi.nlm.nih.gov/pubmed/32317682 http://dx.doi.org/10.1038/s41598-020-63614-3 |
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author | Gambari, M. Clady, R. Stolidi, A. Utéza, O. Sentis, M. Ferré, A. |
author_facet | Gambari, M. Clady, R. Stolidi, A. Utéza, O. Sentis, M. Ferré, A. |
author_sort | Gambari, M. |
collection | PubMed |
description | This study explores the ability of a hard K(α) x-ray source (17.48 keV) produced by a 10 TW class laser system operated at high temporal contrast ratio and high repetition rate for phase contrast imaging. For demonstration, a parametric study based on a known object (PET films) shows clear evidence of feasibility of phase contrast imaging over a large range of laser intensity on target (from ~10(17) W/cm(2) to 7.0 × 10(18) W/cm(2)). To highlight this result, a comparison of raw phase contrast and retrieved phase images of a biological object (a wasp) is done at different laser intensities below the relativistic intensity regime and up to 1.3 × 10(19) W/cm(2). This brings out attractive imaging strategies by selecting suitable laser intensity for optimizing either high spatial resolution and high quality of image or short acquisition time. |
format | Online Article Text |
id | pubmed-7174335 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-71743352020-04-24 Exploring phase contrast imaging with a laser-based K(α) x-ray source up to relativistic laser intensity Gambari, M. Clady, R. Stolidi, A. Utéza, O. Sentis, M. Ferré, A. Sci Rep Article This study explores the ability of a hard K(α) x-ray source (17.48 keV) produced by a 10 TW class laser system operated at high temporal contrast ratio and high repetition rate for phase contrast imaging. For demonstration, a parametric study based on a known object (PET films) shows clear evidence of feasibility of phase contrast imaging over a large range of laser intensity on target (from ~10(17) W/cm(2) to 7.0 × 10(18) W/cm(2)). To highlight this result, a comparison of raw phase contrast and retrieved phase images of a biological object (a wasp) is done at different laser intensities below the relativistic intensity regime and up to 1.3 × 10(19) W/cm(2). This brings out attractive imaging strategies by selecting suitable laser intensity for optimizing either high spatial resolution and high quality of image or short acquisition time. Nature Publishing Group UK 2020-04-21 /pmc/articles/PMC7174335/ /pubmed/32317682 http://dx.doi.org/10.1038/s41598-020-63614-3 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Gambari, M. Clady, R. Stolidi, A. Utéza, O. Sentis, M. Ferré, A. Exploring phase contrast imaging with a laser-based K(α) x-ray source up to relativistic laser intensity |
title | Exploring phase contrast imaging with a laser-based K(α) x-ray source up to relativistic laser intensity |
title_full | Exploring phase contrast imaging with a laser-based K(α) x-ray source up to relativistic laser intensity |
title_fullStr | Exploring phase contrast imaging with a laser-based K(α) x-ray source up to relativistic laser intensity |
title_full_unstemmed | Exploring phase contrast imaging with a laser-based K(α) x-ray source up to relativistic laser intensity |
title_short | Exploring phase contrast imaging with a laser-based K(α) x-ray source up to relativistic laser intensity |
title_sort | exploring phase contrast imaging with a laser-based k(α) x-ray source up to relativistic laser intensity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174335/ https://www.ncbi.nlm.nih.gov/pubmed/32317682 http://dx.doi.org/10.1038/s41598-020-63614-3 |
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