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Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis
Collagen-producing cells maintain the complex architecture of the lung and drive pathologic scarring in pulmonary fibrosis. Here we perform single-cell RNA-sequencing to identify all collagen-producing cells in normal and fibrotic lungs. We characterize multiple collagen-producing subpopulations wit...
Autores principales: | Tsukui, Tatsuya, Sun, Kai-Hui, Wetter, Joseph B., Wilson-Kanamori, John R., Hazelwood, Lisa A., Henderson, Neil C., Adams, Taylor S., Schupp, Jonas C., Poli, Sergio D., Rosas, Ivan O., Kaminski, Naftali, Matthay, Michael A., Wolters, Paul J., Sheppard, Dean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174390/ https://www.ncbi.nlm.nih.gov/pubmed/32317643 http://dx.doi.org/10.1038/s41467-020-15647-5 |
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