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CD73's Potential as an Immunotherapy Target in Gastrointestinal Cancers

CD73, a cell surface 5′nucleotidase that generates adenosine, has emerged as an attractive therapeutic target for reprogramming cancer cells and the tumor microenvironment to dampen antitumor immune cell evasion. Decades of studies have paved the way for these findings, starting with the discovery o...

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Detalles Bibliográficos
Autores principales: Harvey, Jerry B., Phan, Luan H., Villarreal, Oscar E., Bowser, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174602/
https://www.ncbi.nlm.nih.gov/pubmed/32351498
http://dx.doi.org/10.3389/fimmu.2020.00508