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Incorporating Phylogenetic Information in Microbiome Differential Abundance Studies Has No Effect on Detection Power and FDR Control

We consider the problem of incorporating evolutionary information (e.g., taxonomic or phylogenic trees) in the context of metagenomics differential analysis. Recent results published in the literature propose different ways to leverage the tree structure to increase the detection rate of differentia...

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Detalles Bibliográficos
Autores principales: Bichat, Antoine, Plassais, Jonathan, Ambroise, Christophe, Mariadassou, Mahendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174607/
https://www.ncbi.nlm.nih.gov/pubmed/32351481
http://dx.doi.org/10.3389/fmicb.2020.00649