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Picroside II Improves Severe Acute Pancreatitis-Induced Intestinal Barrier Injury by Inactivating Oxidative and Inflammatory TLR4-Dependent PI3K/AKT/NF-κB Signaling and Improving Gut Microbiota
BACKGROUND: Picroside II exerts anti-inflammatory and antidiarrheal effects for treating the diseases associated with oxidative injury. However, its function on pancreatitis-induced intestinal barrier injury remains unclear. Hypothesis/Purpose. We hypothesized that picroside II will have protective...
Autores principales: | Piao, Xuehua, Liu, Baohai, Sui, Xiaodan, Li, Shuangdi, Niu, Wei, Zhang, Qingyu, Shi, Xuan, Cai, Shusheng, Fan, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174951/ https://www.ncbi.nlm.nih.gov/pubmed/32351672 http://dx.doi.org/10.1155/2020/3589497 |
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