Reprogramming the Constant Region of Immunoglobulin G Subclasses for Enhanced Therapeutic Potency against Cancer

The constant region of immunoglobulin (Ig) G antibodies is responsible for their effector immune mechanism and prolongs serum half-life, while the fragment variable (Fv) region is responsible for cellular or tissue targeting. Therefore, antibody engineering for cancer therapeutics focuses on both fu...

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Detalles Bibliográficos
Autores principales: Kang, Tae Hyun, Jung, Sang Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175108/
https://www.ncbi.nlm.nih.gov/pubmed/32121592
http://dx.doi.org/10.3390/biom10030382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175108/
https://www.ncbi.nlm.nih.gov/pubmed/32121592
http://dx.doi.org/10.3390/biom10030382

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