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Rational Engineering of the Substrate Specificity of a Thermostable D-Hydantoinase (Dihydropyrimidinase)

D-hydantoinases catalyze an enantioselective opening of 5- and 6-membered cyclic structures and therefore can be used for the production of optically pure precursors for biomedical applications. The thermostable D-hydantoinase from Geobacillus stearothermophilus ATCC 31783 is a manganese-dependent e...

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Detalles Bibliográficos
Autores principales:	Aganyants, Hovsep, Weigel, Pierre, Hovhannisyan, Yeranuhi, Lecocq, Michèle, Koloyan, Haykanush, Hambardzumyan, Artur, Hovsepyan, Anichka, Hallet, Jean-Noël, Sakanyan, Vehary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175128/ https://www.ncbi.nlm.nih.gov/pubmed/32059545 http://dx.doi.org/10.3390/ht9010005

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