A Protein in the Yeast Saccharomyces cerevisiae Presents DNA Binding Homology to the p53 Checkpoint Protein and Tumor Suppressor

Saccharomyces cerevisiae does not contain a p53 homolog. Utilizing this yeast as an in vivo test tube model, our aim was to investigate if a yeast protein would show p53 DNA binding homology. Electrophoretic mobility shift analyses revealed the formation of specific DNA-protein complexes consisting...

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Detalles Bibliográficos
Autores principales: Farooqi, Kanwal, Ghazvini, Marjan, Pride, Leah D., Mazzella, Louis, White, David, Pramanik, Ajay, Bargonetti, Jill, Moore, Carol Wood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175211/
https://www.ncbi.nlm.nih.gov/pubmed/32156076
http://dx.doi.org/10.3390/biom10030417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175211/
https://www.ncbi.nlm.nih.gov/pubmed/32156076
http://dx.doi.org/10.3390/biom10030417

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