Cargando…

Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020)

In article number https://doi.org/10.1002/advs.201903307, Cun Zhang, Wei Wu, and co‐workers identify the adult perivascular adipose tissue (PVAT) as the dominant source of vascular progenitors in a rat abdominal aorta model and clarify the mechanism by which DTβ4 enhances arterial muscle remodeling...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Wanli, Jia, Sansan, Zhang, Xinchi, Zhang, Siqian, Liu, Huan, Yang, Xin, Zhang, Cun, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175263/
http://dx.doi.org/10.1002/advs.202070045
_version_ 1783524797253156864
author Chen, Wanli
Jia, Sansan
Zhang, Xinchi
Zhang, Siqian
Liu, Huan
Yang, Xin
Zhang, Cun
Wu, Wei
author_facet Chen, Wanli
Jia, Sansan
Zhang, Xinchi
Zhang, Siqian
Liu, Huan
Yang, Xin
Zhang, Cun
Wu, Wei
author_sort Chen, Wanli
collection PubMed
description In article number https://doi.org/10.1002/advs.201903307, Cun Zhang, Wei Wu, and co‐workers identify the adult perivascular adipose tissue (PVAT) as the dominant source of vascular progenitors in a rat abdominal aorta model and clarify the mechanism by which DTβ4 enhances arterial muscle remodeling in the aging body. Different from conventional synthetic grafts, DTβ4‐incorporated grafts exhibit enhanced vascular regenerative activity and effectively ameliorate aging induced defective regeneration, thus providing a rational strategy for clinical translation of vascular grafts. [Image: see text]
format Online
Article
Text
id pubmed-7175263
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-71752632020-04-23 Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020) Chen, Wanli Jia, Sansan Zhang, Xinchi Zhang, Siqian Liu, Huan Yang, Xin Zhang, Cun Wu, Wei Adv Sci (Weinh) Back Cover In article number https://doi.org/10.1002/advs.201903307, Cun Zhang, Wei Wu, and co‐workers identify the adult perivascular adipose tissue (PVAT) as the dominant source of vascular progenitors in a rat abdominal aorta model and clarify the mechanism by which DTβ4 enhances arterial muscle remodeling in the aging body. Different from conventional synthetic grafts, DTβ4‐incorporated grafts exhibit enhanced vascular regenerative activity and effectively ameliorate aging induced defective regeneration, thus providing a rational strategy for clinical translation of vascular grafts. [Image: see text] John Wiley and Sons Inc. 2020-04-22 /pmc/articles/PMC7175263/ http://dx.doi.org/10.1002/advs.202070045 Text en © 2020 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Back Cover
Chen, Wanli
Jia, Sansan
Zhang, Xinchi
Zhang, Siqian
Liu, Huan
Yang, Xin
Zhang, Cun
Wu, Wei
Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020)
title Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020)
title_full Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020)
title_fullStr Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020)
title_full_unstemmed Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020)
title_short Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020)
title_sort arterial regeneration: dimeric thymosin β4 loaded nanofibrous interface enhanced regeneration of muscular artery in aging body through modulating perivascular adipose stem cell–macrophage interaction (adv. sci. 8/2020)
topic Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175263/
http://dx.doi.org/10.1002/advs.202070045
work_keys_str_mv AT chenwanli arterialregenerationdimericthymosinb4loadednanofibrousinterfaceenhancedregenerationofmusculararteryinagingbodythroughmodulatingperivascularadiposestemcellmacrophageinteractionadvsci82020
AT jiasansan arterialregenerationdimericthymosinb4loadednanofibrousinterfaceenhancedregenerationofmusculararteryinagingbodythroughmodulatingperivascularadiposestemcellmacrophageinteractionadvsci82020
AT zhangxinchi arterialregenerationdimericthymosinb4loadednanofibrousinterfaceenhancedregenerationofmusculararteryinagingbodythroughmodulatingperivascularadiposestemcellmacrophageinteractionadvsci82020
AT zhangsiqian arterialregenerationdimericthymosinb4loadednanofibrousinterfaceenhancedregenerationofmusculararteryinagingbodythroughmodulatingperivascularadiposestemcellmacrophageinteractionadvsci82020
AT liuhuan arterialregenerationdimericthymosinb4loadednanofibrousinterfaceenhancedregenerationofmusculararteryinagingbodythroughmodulatingperivascularadiposestemcellmacrophageinteractionadvsci82020
AT yangxin arterialregenerationdimericthymosinb4loadednanofibrousinterfaceenhancedregenerationofmusculararteryinagingbodythroughmodulatingperivascularadiposestemcellmacrophageinteractionadvsci82020
AT zhangcun arterialregenerationdimericthymosinb4loadednanofibrousinterfaceenhancedregenerationofmusculararteryinagingbodythroughmodulatingperivascularadiposestemcellmacrophageinteractionadvsci82020
AT wuwei arterialregenerationdimericthymosinb4loadednanofibrousinterfaceenhancedregenerationofmusculararteryinagingbodythroughmodulatingperivascularadiposestemcellmacrophageinteractionadvsci82020