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Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020)
In article number https://doi.org/10.1002/advs.201903307, Cun Zhang, Wei Wu, and co‐workers identify the adult perivascular adipose tissue (PVAT) as the dominant source of vascular progenitors in a rat abdominal aorta model and clarify the mechanism by which DTβ4 enhances arterial muscle remodeling...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175263/ http://dx.doi.org/10.1002/advs.202070045 |
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author | Chen, Wanli Jia, Sansan Zhang, Xinchi Zhang, Siqian Liu, Huan Yang, Xin Zhang, Cun Wu, Wei |
author_facet | Chen, Wanli Jia, Sansan Zhang, Xinchi Zhang, Siqian Liu, Huan Yang, Xin Zhang, Cun Wu, Wei |
author_sort | Chen, Wanli |
collection | PubMed |
description | In article number https://doi.org/10.1002/advs.201903307, Cun Zhang, Wei Wu, and co‐workers identify the adult perivascular adipose tissue (PVAT) as the dominant source of vascular progenitors in a rat abdominal aorta model and clarify the mechanism by which DTβ4 enhances arterial muscle remodeling in the aging body. Different from conventional synthetic grafts, DTβ4‐incorporated grafts exhibit enhanced vascular regenerative activity and effectively ameliorate aging induced defective regeneration, thus providing a rational strategy for clinical translation of vascular grafts. [Image: see text] |
format | Online Article Text |
id | pubmed-7175263 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71752632020-04-23 Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020) Chen, Wanli Jia, Sansan Zhang, Xinchi Zhang, Siqian Liu, Huan Yang, Xin Zhang, Cun Wu, Wei Adv Sci (Weinh) Back Cover In article number https://doi.org/10.1002/advs.201903307, Cun Zhang, Wei Wu, and co‐workers identify the adult perivascular adipose tissue (PVAT) as the dominant source of vascular progenitors in a rat abdominal aorta model and clarify the mechanism by which DTβ4 enhances arterial muscle remodeling in the aging body. Different from conventional synthetic grafts, DTβ4‐incorporated grafts exhibit enhanced vascular regenerative activity and effectively ameliorate aging induced defective regeneration, thus providing a rational strategy for clinical translation of vascular grafts. [Image: see text] John Wiley and Sons Inc. 2020-04-22 /pmc/articles/PMC7175263/ http://dx.doi.org/10.1002/advs.202070045 Text en © 2020 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Back Cover Chen, Wanli Jia, Sansan Zhang, Xinchi Zhang, Siqian Liu, Huan Yang, Xin Zhang, Cun Wu, Wei Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020) |
title | Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020) |
title_full | Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020) |
title_fullStr | Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020) |
title_full_unstemmed | Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020) |
title_short | Arterial Regeneration: Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction (Adv. Sci. 8/2020) |
title_sort | arterial regeneration: dimeric thymosin β4 loaded nanofibrous interface enhanced regeneration of muscular artery in aging body through modulating perivascular adipose stem cell–macrophage interaction (adv. sci. 8/2020) |
topic | Back Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175263/ http://dx.doi.org/10.1002/advs.202070045 |
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