Cargando…

Polyphenolic Compounds from Lespedeza Bicolor Root Bark Inhibit Progression of Human Prostate Cancer Cells via Induction of Apoptosis and Cell Cycle Arrest

From a root bark of Lespedeza bicolor Turch we isolated two new (7 and 8) and six previously known compounds (1–6) belonging to the group of prenylated polyphenols. Their structures were elucidated using mass spectrometry, nuclear magnetic resonance and circular dichroism spectroscopy. These natural...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dyshlovoy, Sergey A., Tarbeeva, Darya, Fedoreyev, Sergey, Busenbender, Tobias, Kaune, Moritz, Veselova, Marina, Kalinovskiy, Anatoliy, Hauschild, Jessica, Grigorchuk, Valeria, Kim, Natalya, Bokemeyer, Carsten, Graefen, Markus, Gorovoy, Petr, von Amsberg, Gunhild
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175281/ https://www.ncbi.nlm.nih.gov/pubmed/32183314 http://dx.doi.org/10.3390/biom10030451

Ejemplares similares

Polyphenolic Compounds from Lespedeza bicolor Protect Neuronal Cells from Oxidative Stress
por: Tarbeeva, Darya V., et al.
Publicado: (2022)

Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2021)

Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2022)

Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

Neuroprotective and Antiherpetic Properties of Polyphenolic Compounds from Maackia amurensis Heartwood
por: Tarbeeva, Darya V., et al.
Publicado: (2023)

Immunotherapy in Advanced Prostate Cancer—Light at the End of the Tunnel?
por: von Amsberg, Gunhild, et al.
Publicado: (2022)

New Marine Fungal Deoxy-14,15-Dehydroisoaustamide Resensitizes Prostate Cancer Cells to Enzalutamide
por: Dyshlovoy, Sergey A., et al.
Publicado: (2023)

Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

Study of Structure–Activity Relationships of the Marine Alkaloid Fascaplysin and Its Derivatives as Potent Anticancer Agents
por: Zhidkov, Maxim E., et al.
Publicado: (2022)

Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones
por: Dyshlovoy, Sergey A., et al.
Publicado: (2019)

New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein
por: Dyshlovoy, Sergey A., et al.
Publicado: (2022)

Therapeutic Potential of Lespedeza bicolor to Prevent Methylglyoxal-Induced Glucotoxicity in Familiar Diabetic Nephropathy
por: Do, Moon Ho, et al.
Publicado: (2019)

Total Syntheses and Preliminary Biological Evaluation of Brominated Fascaplysin and Reticulatine Alkaloids and Their Analogues
por: Zhidkov, Maxim E., et al.
Publicado: (2019)

New Bioactive β-Resorcylic Acid Derivatives from the Alga-Derived Fungus Penicillium antarcticum KMM 4685
por: Leshchenko, Elena V., et al.
Publicado: (2023)

Aaptamines from the Marine Sponge Aaptos sp. Display Anticancer Activities in Human Cancer Cell Lines and Modulate AP-1-, NF-κB-, and p53-Dependent Transcriptional Activity in Mouse JB6 Cl41 Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2014)

A potential anti-inflammation activity and depigmentation effect of Lespedeza bicolor extract and its fractions
por: Lee, Seung Jin, et al.
Publicado: (2016)

Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer
por: Dyshlovoy, Sergey A., et al.
Publicado: (2018)

Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer
por: von Amsberg, Gunhild, et al.
Publicado: (2022)

Antioxidant Polyphenols from Lespedeza bicolor Turcz. Honey: Anti-Inflammatory Effects on Lipopolysaccharide-Treated RAW 264.7 Macrophages
por: Ren, Caijun, et al.
Publicado: (2023)

New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge Monanchora pulchra Induce Apoptosis and Autophagy in Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2022)

Effects of Lespedeza Bicolor Extract on Regulation of AMPK Associated Hepatic Lipid Metabolism in Type 2 Diabetic Mice
por: Kim, Younmi, et al.
Publicado: (2019)

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2017)

Lespedeza bicolor Extract Ameliorated Renal Inflammation by Regulation of NLRP3 Inflammasome-Associated Hyperinflammation in Type 2 Diabetic Mice
por: Park, Ji Eun, et al.
Publicado: (2020)

Sea Anemone Heteractis crispa Actinoporin Demonstrates In Vitro Anticancer Activities and Prevents HT-29 Colorectal Cancer Cell Migration
por: Kvetkina, Aleksandra, et al.
Publicado: (2020)

The Inhibitory Activity of Luzonicosides from the Starfish Echinaster luzonicus against Human Melanoma Cells
por: Malyarenko, Olesya S., et al.
Publicado: (2017)

Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization
por: Dyshlovoy, Sergey A., et al.
Publicado: (2015)

Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro
por: Dyshlovoy, Sergey A., et al.
Publicado: (2016)

New Trisulfated Steroids from the Vietnamese Marine Sponge Halichondria vansoesti and Their PSA Expression and Glucose Uptake Inhibitory Activities
por: Tabakmakher, Kseniya M., et al.
Publicado: (2019)

Pretrichodermamides D–F from a Marine Algicolous Fungus Penicillium sp. KMM 4672
por: Yurchenko, Anton N., et al.
Publicado: (2016)

1-O-Alkylglycerol Ethers from the Marine Sponge Guitarra abbotti and Their Cytotoxic Activity
por: Dyshlovoy, Sergey A., et al.
Publicado: (2022)

Cytotoxic Marine Alkaloid 3,10-Dibromofascaplysin Induces Apoptosis and Synergizes with Cytarabine Resulting in Leukemia Cell Death
por: Spirin, Pavel, et al.
Publicado: (2021)

Maackia amurensis Rupr. et Maxim.: Supercritical CO(2) Extraction and Mass Spectrometric Characterization of Chemical Constituents
por: Razgonova, Mayya P., et al.
Publicado: (2023)

Antiviral Potential of Sea Urchin Aminated Spinochromes against Herpes Simplex Virus Type 1
por: Mishchenko, Natalia P., et al.
Publicado: (2020)

A New Mild Method for Synthesis of Marine Alkaloid Fascaplysin and Its Therapeutically Promising Derivatives
por: Tryapkin, Oleg A., et al.
Publicado: (2023)

Isolation and Structure Determination of Echinochrome A Oxidative Degradation Products
por: Mishchenko, Natalia P., et al.
Publicado: (2020)

The complete chloroplast genome sequence of Lespedeza buergeri Miq. (Fabaceae)
por: Wang, Shuting, et al.
Publicado: (2022)

Gracilosulfates A–G, Monosulfated Polyoxygenated Steroids from the Marine Sponge Haliclona gracilis
por: Shubina, Larisa K., et al.
Publicado: (2020)

Pathophysiology and transcriptomic analysis of Picea koraiensis inoculated by bark beetle-vectored fungus Ophiostoma bicolor
por: Liu, Ya, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hrlh60d0kvptemdhjvo1iesumj