Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children

This study evaluates salivary immunoglobulin A (s-IgA) and interleukin 6 (IL-6) in saliva of children and its correlation to tooth decay severity. Fifty-nine patients were divided into two groups: caries free (A group) and caries active (B group). B group was investigated according to Mount and Mons...

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Autores principales: Lo Giudice, Giuseppe, Nicita, Fabiana, Militi, Angela, Bertino, Rossella, Matarese, Marco, Currò, Monica, Damiano, Carmelo Salpietro, Mannucci, Carmen, Calapai, Gioacchino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175292/
https://www.ncbi.nlm.nih.gov/pubmed/31892186
http://dx.doi.org/10.3390/dj8010003
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author Lo Giudice, Giuseppe
Nicita, Fabiana
Militi, Angela
Bertino, Rossella
Matarese, Marco
Currò, Monica
Damiano, Carmelo Salpietro
Mannucci, Carmen
Calapai, Gioacchino
author_facet Lo Giudice, Giuseppe
Nicita, Fabiana
Militi, Angela
Bertino, Rossella
Matarese, Marco
Currò, Monica
Damiano, Carmelo Salpietro
Mannucci, Carmen
Calapai, Gioacchino
author_sort Lo Giudice, Giuseppe
collection PubMed
description This study evaluates salivary immunoglobulin A (s-IgA) and interleukin 6 (IL-6) in saliva of children and its correlation to tooth decay severity. Fifty-nine patients were divided into two groups: caries free (A group) and caries active (B group). B group was investigated according to Mount and Monse indices. Mean salivary IgA rate between two groups (A 16.7 ± 4.5 mg/dL vs. B 21.8 ± 12.9 mg/dL) was not significant, while IL-6 rate (A 19.02 ± 5.3 pg/mL vs. B 30.2 ± 11.8 pg/mL) was statistically different. This study revealed that salivary IL-6 levels were significantly higher in children with active caries when compared with the caries-free group, while the s-IgA rate showed no significant differences between the two groups.
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spelling pubmed-71752922020-04-28 Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children Lo Giudice, Giuseppe Nicita, Fabiana Militi, Angela Bertino, Rossella Matarese, Marco Currò, Monica Damiano, Carmelo Salpietro Mannucci, Carmen Calapai, Gioacchino Dent J (Basel) Article This study evaluates salivary immunoglobulin A (s-IgA) and interleukin 6 (IL-6) in saliva of children and its correlation to tooth decay severity. Fifty-nine patients were divided into two groups: caries free (A group) and caries active (B group). B group was investigated according to Mount and Monse indices. Mean salivary IgA rate between two groups (A 16.7 ± 4.5 mg/dL vs. B 21.8 ± 12.9 mg/dL) was not significant, while IL-6 rate (A 19.02 ± 5.3 pg/mL vs. B 30.2 ± 11.8 pg/mL) was statistically different. This study revealed that salivary IL-6 levels were significantly higher in children with active caries when compared with the caries-free group, while the s-IgA rate showed no significant differences between the two groups. MDPI 2019-12-27 /pmc/articles/PMC7175292/ /pubmed/31892186 http://dx.doi.org/10.3390/dj8010003 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lo Giudice, Giuseppe
Nicita, Fabiana
Militi, Angela
Bertino, Rossella
Matarese, Marco
Currò, Monica
Damiano, Carmelo Salpietro
Mannucci, Carmen
Calapai, Gioacchino
Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children
title Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children
title_full Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children
title_fullStr Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children
title_full_unstemmed Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children
title_short Correlation of s-IgA and IL-6 Salivary with Caries Disease and Oral Hygiene Parameters in Children
title_sort correlation of s-iga and il-6 salivary with caries disease and oral hygiene parameters in children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175292/
https://www.ncbi.nlm.nih.gov/pubmed/31892186
http://dx.doi.org/10.3390/dj8010003
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