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Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)
In article number https://doi.org/10.1002/advs.201902802, David B. Weiner, Daniel W. Kulp, and co‐workers demonstrate that synthetic DNA delivery and adaptive electroporation can launch de novo assembly of different nanoparticle vaccines in the hosts to elicit significantly improved responses while...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175322/ http://dx.doi.org/10.1002/advs.202070044 |
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author | Xu, Ziyang Wise, Megan C. Chokkalingam, Neethu Walker, Susanne Tello‐Ruiz, Edgar Elliott, Sarah T. C. Perales‐Puchalt, Alfredo Xiao, Peng Zhu, Xizhou Pumroy, Ruth A. Fisher, Paul D. Schultheis, Katherine Schade, Eric Menis, Sergey Guzman, Stacy Andersen, Hanne Broderick, Kate E. Humeau, Laurent M. Muthumani, Kar Moiseenkova‐Bell, Vera Schief, William R. Weiner, David B. Kulp, Daniel W. |
author_facet | Xu, Ziyang Wise, Megan C. Chokkalingam, Neethu Walker, Susanne Tello‐Ruiz, Edgar Elliott, Sarah T. C. Perales‐Puchalt, Alfredo Xiao, Peng Zhu, Xizhou Pumroy, Ruth A. Fisher, Paul D. Schultheis, Katherine Schade, Eric Menis, Sergey Guzman, Stacy Andersen, Hanne Broderick, Kate E. Humeau, Laurent M. Muthumani, Kar Moiseenkova‐Bell, Vera Schief, William R. Weiner, David B. Kulp, Daniel W. |
author_sort | Xu, Ziyang |
collection | PubMed |
description | In article number https://doi.org/10.1002/advs.201902802, David B. Weiner, Daniel W. Kulp, and co‐workers demonstrate that synthetic DNA delivery and adaptive electroporation can launch de novo assembly of different nanoparticle vaccines in the hosts to elicit significantly improved responses while reducing required doses. Next‐generation designer vaccines can now be rapidly evaluated in vivo to facilitate clinical translation for the betterment of human and animal health. [Image: see text] |
format | Online Article Text |
id | pubmed-7175322 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71753222020-04-23 Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) Xu, Ziyang Wise, Megan C. Chokkalingam, Neethu Walker, Susanne Tello‐Ruiz, Edgar Elliott, Sarah T. C. Perales‐Puchalt, Alfredo Xiao, Peng Zhu, Xizhou Pumroy, Ruth A. Fisher, Paul D. Schultheis, Katherine Schade, Eric Menis, Sergey Guzman, Stacy Andersen, Hanne Broderick, Kate E. Humeau, Laurent M. Muthumani, Kar Moiseenkova‐Bell, Vera Schief, William R. Weiner, David B. Kulp, Daniel W. Adv Sci (Weinh) Inside Back Cover In article number https://doi.org/10.1002/advs.201902802, David B. Weiner, Daniel W. Kulp, and co‐workers demonstrate that synthetic DNA delivery and adaptive electroporation can launch de novo assembly of different nanoparticle vaccines in the hosts to elicit significantly improved responses while reducing required doses. Next‐generation designer vaccines can now be rapidly evaluated in vivo to facilitate clinical translation for the betterment of human and animal health. [Image: see text] John Wiley and Sons Inc. 2020-04-22 /pmc/articles/PMC7175322/ http://dx.doi.org/10.1002/advs.202070044 Text en © 2020 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Inside Back Cover Xu, Ziyang Wise, Megan C. Chokkalingam, Neethu Walker, Susanne Tello‐Ruiz, Edgar Elliott, Sarah T. C. Perales‐Puchalt, Alfredo Xiao, Peng Zhu, Xizhou Pumroy, Ruth A. Fisher, Paul D. Schultheis, Katherine Schade, Eric Menis, Sergey Guzman, Stacy Andersen, Hanne Broderick, Kate E. Humeau, Laurent M. Muthumani, Kar Moiseenkova‐Bell, Vera Schief, William R. Weiner, David B. Kulp, Daniel W. Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) |
title | Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) |
title_full | Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) |
title_fullStr | Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) |
title_full_unstemmed | Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) |
title_short | Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) |
title_sort | nanoparticle vaccines: in vivo assembly of nanoparticles achieved through synergy of structure‐based protein engineering and synthetic dna generates enhanced adaptive immunity (adv. sci. 8/2020) |
topic | Inside Back Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175322/ http://dx.doi.org/10.1002/advs.202070044 |
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