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Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)

In article number https://doi.org/10.1002/advs.201902802, David B. Weiner, Daniel W. Kulp, and co‐workers demonstrate that synthetic DNA delivery and adaptive electroporation can launch de novo assembly of different nanoparticle vaccines in the hosts to elicit significantly improved responses while...

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Autores principales: Xu, Ziyang, Wise, Megan C., Chokkalingam, Neethu, Walker, Susanne, Tello‐Ruiz, Edgar, Elliott, Sarah T. C., Perales‐Puchalt, Alfredo, Xiao, Peng, Zhu, Xizhou, Pumroy, Ruth A., Fisher, Paul D., Schultheis, Katherine, Schade, Eric, Menis, Sergey, Guzman, Stacy, Andersen, Hanne, Broderick, Kate E., Humeau, Laurent M., Muthumani, Kar, Moiseenkova‐Bell, Vera, Schief, William R., Weiner, David B., Kulp, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175322/
http://dx.doi.org/10.1002/advs.202070044
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author Xu, Ziyang
Wise, Megan C.
Chokkalingam, Neethu
Walker, Susanne
Tello‐Ruiz, Edgar
Elliott, Sarah T. C.
Perales‐Puchalt, Alfredo
Xiao, Peng
Zhu, Xizhou
Pumroy, Ruth A.
Fisher, Paul D.
Schultheis, Katherine
Schade, Eric
Menis, Sergey
Guzman, Stacy
Andersen, Hanne
Broderick, Kate E.
Humeau, Laurent M.
Muthumani, Kar
Moiseenkova‐Bell, Vera
Schief, William R.
Weiner, David B.
Kulp, Daniel W.
author_facet Xu, Ziyang
Wise, Megan C.
Chokkalingam, Neethu
Walker, Susanne
Tello‐Ruiz, Edgar
Elliott, Sarah T. C.
Perales‐Puchalt, Alfredo
Xiao, Peng
Zhu, Xizhou
Pumroy, Ruth A.
Fisher, Paul D.
Schultheis, Katherine
Schade, Eric
Menis, Sergey
Guzman, Stacy
Andersen, Hanne
Broderick, Kate E.
Humeau, Laurent M.
Muthumani, Kar
Moiseenkova‐Bell, Vera
Schief, William R.
Weiner, David B.
Kulp, Daniel W.
author_sort Xu, Ziyang
collection PubMed
description In article number https://doi.org/10.1002/advs.201902802, David B. Weiner, Daniel W. Kulp, and co‐workers demonstrate that synthetic DNA delivery and adaptive electroporation can launch de novo assembly of different nanoparticle vaccines in the hosts to elicit significantly improved responses while reducing required doses. Next‐generation designer vaccines can now be rapidly evaluated in vivo to facilitate clinical translation for the betterment of human and animal health. [Image: see text]
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spelling pubmed-71753222020-04-23 Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020) Xu, Ziyang Wise, Megan C. Chokkalingam, Neethu Walker, Susanne Tello‐Ruiz, Edgar Elliott, Sarah T. C. Perales‐Puchalt, Alfredo Xiao, Peng Zhu, Xizhou Pumroy, Ruth A. Fisher, Paul D. Schultheis, Katherine Schade, Eric Menis, Sergey Guzman, Stacy Andersen, Hanne Broderick, Kate E. Humeau, Laurent M. Muthumani, Kar Moiseenkova‐Bell, Vera Schief, William R. Weiner, David B. Kulp, Daniel W. Adv Sci (Weinh) Inside Back Cover In article number https://doi.org/10.1002/advs.201902802, David B. Weiner, Daniel W. Kulp, and co‐workers demonstrate that synthetic DNA delivery and adaptive electroporation can launch de novo assembly of different nanoparticle vaccines in the hosts to elicit significantly improved responses while reducing required doses. Next‐generation designer vaccines can now be rapidly evaluated in vivo to facilitate clinical translation for the betterment of human and animal health. [Image: see text] John Wiley and Sons Inc. 2020-04-22 /pmc/articles/PMC7175322/ http://dx.doi.org/10.1002/advs.202070044 Text en © 2020 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Back Cover
Xu, Ziyang
Wise, Megan C.
Chokkalingam, Neethu
Walker, Susanne
Tello‐Ruiz, Edgar
Elliott, Sarah T. C.
Perales‐Puchalt, Alfredo
Xiao, Peng
Zhu, Xizhou
Pumroy, Ruth A.
Fisher, Paul D.
Schultheis, Katherine
Schade, Eric
Menis, Sergey
Guzman, Stacy
Andersen, Hanne
Broderick, Kate E.
Humeau, Laurent M.
Muthumani, Kar
Moiseenkova‐Bell, Vera
Schief, William R.
Weiner, David B.
Kulp, Daniel W.
Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)
title Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)
title_full Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)
title_fullStr Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)
title_full_unstemmed Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)
title_short Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv. Sci. 8/2020)
title_sort nanoparticle vaccines: in vivo assembly of nanoparticles achieved through synergy of structure‐based protein engineering and synthetic dna generates enhanced adaptive immunity (adv. sci. 8/2020)
topic Inside Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175322/
http://dx.doi.org/10.1002/advs.202070044
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