Cargando…

Proteomic Analysis of Mucopolysaccharidosis IIIB Mouse Brain

Mucopolysaccharidosis IIIB (MPS IIIB) is an inherited metabolic disease due to deficiency of α-N-Acetylglucosaminidase (NAGLU) enzyme with subsequent storage of undegraded heparan sulfate (HS). The main clinical manifestations of the disease are profound intellectual disability and neurodegeneration...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Pasquale, Valeria, Costanzo, Michele, Siciliano, Rosa Anna, Mazzeo, Maria Fiorella, Pistorio, Valeria, Bianchi, Laura, Marchese, Emanuela, Ruoppolo, Margherita, Pavone, Luigi Michele, Caterino, Marianna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175334/ https://www.ncbi.nlm.nih.gov/pubmed/32111039 http://dx.doi.org/10.3390/biom10030355

Ejemplares similares

Targeted Metabolomic Analysis of a Mucopolysaccharidosis IIIB Mouse Model Reveals an Imbalance of Branched-Chain Amino Acid and Fatty Acid Metabolism
por: De Pasquale, Valeria, et al.
Publicado: (2020)

Label-Free Quantitative Proteomics in a Methylmalonyl-CoA Mutase-Silenced Neuroblastoma Cell Line
por: Costanzo, Michele, et al.
Publicado: (2018)

Proteome data of neuroblastoma cells overexpressing Neuroglobin
por: Costanzo, Michele, et al.
Publicado: (2022)

EGFR activation triggers cellular hypertrophy and lysosomal disease in NAGLU-depleted cardiomyoblasts, mimicking the hallmarks of mucopolysaccharidosis IIIB
por: De Pasquale, Valeria, et al.
Publicado: (2018)

Aortopathies in mouse models of Pompe, Fabry and Mucopolysaccharidosis IIIB lysosomal storage diseases
por: Belfiore, Maria Paola, et al.
Publicado: (2020)

The Murine Model of Mucopolysaccharidosis IIIB Develops Cardiopathies over Time Leading to Heart Failure
por: Schiattarella, Gabriele Giacomo, et al.
Publicado: (2015)

Proteomic and Bioinformatic Investigation of Altered Pathways in Neuroglobin-Deficient Breast Cancer Cells
por: Costanzo, Michele, et al.
Publicado: (2021)

COVIDomics: The Proteomic and Metabolomic Signatures of COVID-19
por: Costanzo, Michele, et al.
Publicado: (2022)

An Uncommon Presentation of Mucopolysaccharidosis Type IIIb
por: REZAYI, Alireza, et al.
Publicado: (2019)

Influence of Sex on Urinary Organic Acids: A Cross-Sectional Study in Children
por: Caterino, Marianna, et al.
Publicado: (2020)

Mass Spectrometry-Based Metabolomic and Proteomic Strategies in Organic Acidemias
por: Imperlini, Esther, et al.
Publicado: (2016)

Proteomics Reveals that Methylmalonyl-CoA Mutase Modulates Cell Architecture and Increases Susceptibility to Stress
por: Costanzo, Michele, et al.
Publicado: (2020)

Sex differences in the human metabolome
por: Costanzo, Michele, et al.
Publicado: (2022)

A model of mucopolysaccharidosis type IIIB in pigs
por: Yang, Qiang, et al.
Publicado: (2018)

Neuropathology in Mouse Models of Mucopolysaccharidosis Type I, IIIA and IIIB
por: Wilkinson, Fiona L., et al.
Publicado: (2012)

Dataset of a comparative proteomics experiment in a methylmalonyl-CoA mutase knockout HEK 293 cell model
por: Costanzo, Michele, et al.
Publicado: (2020)

Challenges in Metabolomics-Based Tests, Biomarkers Revealed by Metabolomic Analysis, and the Promise of the Application of Metabolomics in Precision Medicine
por: Di Minno, Alessandro, et al.
Publicado: (2022)

Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB
por: Petrova, Ralitsa, et al.
Publicado: (2023)

Activation of Stress Kinases in the Brain of Mucopolysaccharidosis IIIB mice
por: Cecere, Francesca, et al.
Publicado: (2011)

The neurobehavioral phenotype in mucopolysaccharidosis Type IIIB: An exploratory study
por: Shapiro, E., et al.
Publicado: (2016)

Heparan Sulfate, Mucopolysaccharidosis IIIB and Sulfur Metabolism Disorders
por: Kaczor-Kamińska, Marta, et al.
Publicado: (2022)

Targeting Heparan Sulfate Proteoglycans as a Novel Therapeutic Strategy for Mucopolysaccharidoses
por: De Pasquale, Valeria, et al.
Publicado: (2018)

Proteomics for the Investigation of Surface-Exposed Proteins in Probiotics
por: Siciliano, Rosa Anna, et al.
Publicado: (2019)

Overexpression of Neuroglobin Promotes Energy Metabolism and Autophagy Induction in Human Neuroblastoma SH-SY5Y Cells
por: Manganelli, Valeria, et al.
Publicado: (2021)

Mucopolysaccharidosis type IIIB may predominantly present with an attenuated clinical phenotype
por: Valstar, Marlies J., et al.
Publicado: (2010)

Long-term clinical course of a patient with mucopolysaccharidosis type IIIB
por: Kim, Ja Hye, et al.
Publicado: (2016)

An exonic insertion in the NAGLU gene causing Mucopolysaccharidosis IIIB in Schipperke dogs
por: Raj, Karthik, et al.
Publicado: (2020)

Peripheral Nervous System Neuropathology and Progressive Sensory Impairments in a Mouse Model of Mucopolysaccharidosis IIIB
por: Fu, Haiyan, et al.
Publicado: (2012)

Editorial: Proteomics for Studying Foodborne Microorganisms and Their Impact on Food Quality and Human Health
por: Siciliano, Rosa Anna, et al.
Publicado: (2019)

Targeted metabolomic profiling in rat tissues reveals sex differences
por: Ruoppolo, Margherita, et al.
Publicado: (2018)

Case report of Chromosome 3q25 deletion syndrome or Mucopolysaccharidosis IIIB
por: Chang, Yu-Tzu, et al.
Publicado: (2014)

Mucopolysaccharidosis type IIIB: a current review and exploration of the AAV therapy landscape
por: Rouse, Courtney J., et al.
Publicado: (2023)

Sex Affects Human Premature Neonates’ Blood Metabolome According to Gestational Age, Parenteral Nutrition, and Caffeine Treatment
por: Caterino, Marianna, et al.
Publicado: (2021)

Unravelling pathways downstream Sox6 induction in K562 erythroid cells by proteomic analysis
por: Barbarani, Gloria, et al.
Publicado: (2017)

Surface Layer Protein Pattern of Levilactobacillus brevis Strains Investigated by Proteomics
por: Mazzeo, Maria Fiorella, et al.
Publicado: (2022)

Lactobacillus acidophilus—Rutin Interplay Investigated by Proteomics
por: Mazzeo, Maria Fiorella, et al.
Publicado: (2015)

Heparan Sulfate Proteoglycan Signaling in Tumor Microenvironment
por: De Pasquale, Valeria, et al.
Publicado: (2020)

Stratification of Amniotic Fluid Cells and Amniotic Fluid by Sex Opens Up New Perspectives on Fetal Health
por: Campesi, Ilaria, et al.
Publicado: (2023)

Early Neurodegeneration Progresses Independently of Microglial Activation by Heparan Sulfate in the Brain of Mucopolysaccharidosis IIIB Mice
por: Ausseil, Jérôme, et al.
Publicado: (2008)

Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response
por: Killedar, Smruti, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_jakpnngg894oidsc72r83s8ka8