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A Unified Linear Viscoelastic Model of the Cell Nucleus Defines the Mechanical Contributions of Lamins and Chromatin

The cell nucleus is constantly subjected to externally applied forces. During metazoan evolution, the nucleus has been optimized to allow physical deformability while protecting the genome under load. Aberrant nucleus mechanics can alter cell migration across narrow spaces in cancer metastasis and i...

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Detalles Bibliográficos
Autores principales: Wintner, Oren, Hirsch‐Attas, Nivi, Schlossberg, Miriam, Brofman, Fani, Friedman, Roy, Kupervaser, Meital, Kitsberg, Danny, Buxboim, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175345/
https://www.ncbi.nlm.nih.gov/pubmed/32328409
http://dx.doi.org/10.1002/advs.201901222

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