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Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-α

Mevastatin (MVS) has been previously shown to induce heme oxygenase (HO)-1 expression through Nox/ROS-dependent PDGFRα/PI3K/Akt/Nrf2/ARE axis in human pulmonary alveolar epithelial cells (HPAEpiCs). However, alternative signaling pathways might involve in MVS-induced HO-1 expression. We found that t...

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Detalles Bibliográficos
Autores principales:	Yang, Chuen-Mao, Lin, Chih-Chung, Yang, Chien-Chung, Cho, Rou-Ling, Hsiao, Li-Der
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175369/ https://www.ncbi.nlm.nih.gov/pubmed/32121588 http://dx.doi.org/10.3390/biom10030381

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