Disulfide isomerase ERp57 improves the stability and immunogenicity of H3N2 influenza virus hemagglutinin

BACKGROUND: Hemagglutinin (HA), as the surface immunogenic protein, is the most important component of influenza viruses. Previous studies showed that the stability of HA was significant for HA’s immunogenicity, and many efforts have been made to stabilize the expressed HA proteins. METHODS: In this...

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Detalles Bibliográficos
Autores principales: Wu, Jialing, Wang, Yang, Wei, Ying, Xu, Zhichao, Tan, Xin, Wu, Zhihui, Zheng, Jing, Liu, George Dacai, Cao, Yongchang, Xue, Chunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175539/
https://www.ncbi.nlm.nih.gov/pubmed/32316996
http://dx.doi.org/10.1186/s12985-020-01325-x

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