Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia

BACKGROUND: Robust activation of glial cells has been reported to occur particularly during the pathogenesis of bone cancer pain (BCP). Researchers from our group and others have shown that histone deacetylases (HDACs) play a significant role in modulating glia-mediated immune responses; however, it...

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Detalles Bibliográficos
Autores principales: He, Xiao-Tao, Hu, Xiao-Fan, Zhu, Chao, Zhou, Kai-Xiang, Zhao, Wen-Jun, Zhang, Chen, Han, Xiao, Wu, Chang-Le, Wei, Yan-Yan, Wang, Wei, Deng, Jian-Ping, Chen, Fa-Ming, Gu, Ze-Xu, Dong, Yu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175547/
https://www.ncbi.nlm.nih.gov/pubmed/32321538
http://dx.doi.org/10.1186/s12974-020-01740-5

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