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The association between parity and spontaneous preterm birth: a population based study

BACKGROUND: Preterm birth is the leading cause of perinatal mortality and neonatal morbidity worldwide. Many factors have been associated with preterm birth, including parity. The aim of the present study was to investigate associations between parity and risk of spontaneous preterm birth. METHODS:...

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Autores principales: Koullali, Bouchra, van Zijl, Maud D., Kazemier, Brenda M., Oudijk, Martijn A., Mol, Ben W. J., Pajkrt, Eva, Ravelli, Anita C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175552/
https://www.ncbi.nlm.nih.gov/pubmed/32316915
http://dx.doi.org/10.1186/s12884-020-02940-w
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author Koullali, Bouchra
van Zijl, Maud D.
Kazemier, Brenda M.
Oudijk, Martijn A.
Mol, Ben W. J.
Pajkrt, Eva
Ravelli, Anita C. J.
author_facet Koullali, Bouchra
van Zijl, Maud D.
Kazemier, Brenda M.
Oudijk, Martijn A.
Mol, Ben W. J.
Pajkrt, Eva
Ravelli, Anita C. J.
author_sort Koullali, Bouchra
collection PubMed
description BACKGROUND: Preterm birth is the leading cause of perinatal mortality and neonatal morbidity worldwide. Many factors have been associated with preterm birth, including parity. The aim of the present study was to investigate associations between parity and risk of spontaneous preterm birth. METHODS: We conducted a retrospective study including live singleton births (≥22 weeks) of women with a first, second, third, fourth or fifth pregnancy in The Netherlands from 2010 through 2014. Our primary outcome was risk of spontaneous preterm birth < 37 weeks. Secondary outcomes were spontaneous preterm birth < 32 and < 28 weeks. RESULTS: We studied 802,119 pregnancies, including 30,237 pregnancies that ended spontaneously < 37 weeks. We identified an increased risk for spontaneous preterm birth < 37 weeks in nulliparous women (OR 1.95, 95% CI 1.89–2.00) and women in their fifth pregnancy (OR 1.26, 95% CI 1.13–1.41) compared to women in their second pregnancy. Similar results were seen for spontaneous preterm birth < 32 and < 28 weeks. CONCLUSION: Our data show an independent association between nulliparity and spontaneous preterm birth < 37, < 32 and < 28 weeks. Furthermore, we observed an increased risk for spontaneous preterm birth in women in their fifth pregnancy, with highest risk for preterm birth at early gestational age.
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spelling pubmed-71755522020-04-24 The association between parity and spontaneous preterm birth: a population based study Koullali, Bouchra van Zijl, Maud D. Kazemier, Brenda M. Oudijk, Martijn A. Mol, Ben W. J. Pajkrt, Eva Ravelli, Anita C. J. BMC Pregnancy Childbirth Research Article BACKGROUND: Preterm birth is the leading cause of perinatal mortality and neonatal morbidity worldwide. Many factors have been associated with preterm birth, including parity. The aim of the present study was to investigate associations between parity and risk of spontaneous preterm birth. METHODS: We conducted a retrospective study including live singleton births (≥22 weeks) of women with a first, second, third, fourth or fifth pregnancy in The Netherlands from 2010 through 2014. Our primary outcome was risk of spontaneous preterm birth < 37 weeks. Secondary outcomes were spontaneous preterm birth < 32 and < 28 weeks. RESULTS: We studied 802,119 pregnancies, including 30,237 pregnancies that ended spontaneously < 37 weeks. We identified an increased risk for spontaneous preterm birth < 37 weeks in nulliparous women (OR 1.95, 95% CI 1.89–2.00) and women in their fifth pregnancy (OR 1.26, 95% CI 1.13–1.41) compared to women in their second pregnancy. Similar results were seen for spontaneous preterm birth < 32 and < 28 weeks. CONCLUSION: Our data show an independent association between nulliparity and spontaneous preterm birth < 37, < 32 and < 28 weeks. Furthermore, we observed an increased risk for spontaneous preterm birth in women in their fifth pregnancy, with highest risk for preterm birth at early gestational age. BioMed Central 2020-04-21 /pmc/articles/PMC7175552/ /pubmed/32316915 http://dx.doi.org/10.1186/s12884-020-02940-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Koullali, Bouchra
van Zijl, Maud D.
Kazemier, Brenda M.
Oudijk, Martijn A.
Mol, Ben W. J.
Pajkrt, Eva
Ravelli, Anita C. J.
The association between parity and spontaneous preterm birth: a population based study
title The association between parity and spontaneous preterm birth: a population based study
title_full The association between parity and spontaneous preterm birth: a population based study
title_fullStr The association between parity and spontaneous preterm birth: a population based study
title_full_unstemmed The association between parity and spontaneous preterm birth: a population based study
title_short The association between parity and spontaneous preterm birth: a population based study
title_sort association between parity and spontaneous preterm birth: a population based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175552/
https://www.ncbi.nlm.nih.gov/pubmed/32316915
http://dx.doi.org/10.1186/s12884-020-02940-w
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