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Progressive multifocal leukoencephalopathy in a patient post allo-HCT successfully treated with JC virus specific donor lymphocytes
BACKGROUND: Progressive multifocal leukoencephalopathy is a demyelinating CNS disorder. Reactivation of John Cunningham virus leads to oligodendrocyte infection with lysis and consequent axonal loss due to demyelination. Patients usually present with confusion and seizures. Late diagnosis and lack o...
Autores principales: | Steinhardt, M. J., Wiercinska, E., Pham, M., Grigoleit, G. U., Mazzoni, A., Da-Via, M., Zhou, X., Meckel, K., Nickel, K., Duell, J., Krummenast, F. C., Kraus, S., Hopkinson, C., Weissbrich, B., Müllges, W., Stoll, G., Kortüm, K. M., Einsele, H., Bonig, H., Rasche, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175555/ https://www.ncbi.nlm.nih.gov/pubmed/32316991 http://dx.doi.org/10.1186/s12967-020-02337-5 |
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