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Infektionen als Notfall der Onkologie: Übersicht über die aktuellen Leitlinien
BACKGROUND: Patients with oncologic diseases, particularly those with hematologic malignancies, are at an increased risk of common infections and unique treatment-related complications with high mortality and morbidity. The annual incidence and prevalence of cancer in Germany is rising. Although mod...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175641/ https://www.ncbi.nlm.nih.gov/pubmed/32322312 http://dx.doi.org/10.1007/s00740-020-00339-z |
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author | Juarso, Andreas Edwin Kiehl, Malte Buchholz, Markus Weißinger, Florian |
author_facet | Juarso, Andreas Edwin Kiehl, Malte Buchholz, Markus Weißinger, Florian |
author_sort | Juarso, Andreas Edwin |
collection | PubMed |
description | BACKGROUND: Patients with oncologic diseases, particularly those with hematologic malignancies, are at an increased risk of common infections and unique treatment-related complications with high mortality and morbidity. The annual incidence and prevalence of cancer in Germany is rising. Although modern treatments have generally led to improved survival, increasing age, comorbidities, and frailty of the patients require multidisciplinary strategies for handling complex therapeutic concepts and treatment of the associated complications. METHODS: A selective literature search and guidelines from the European Society for Medical Oncology (ESMO), the German Society of Hematology and Medical Oncology (Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie, DGHO), the Infectious Diseases Working Group of the DGHO (Arbeitsgemeinschaft Infektionen in der Hämatologie und Onkologie, AGIHO), and the American Society of Clinical Oncology (ASCO) formed the basis of this study. CONCLUSION: Recognition of severe infections in cancer patients and their discrimination from treatment-associated complications is a challenge. Neutropenic fever is the most frequent infectious emergency in oncology. Early empiric treatment with broad-spectrum antibiotics and escalated diagnostic strategies are needed to successfully treat this vulnerable patient group. In this article, a range of potentially life-threatening infections in immunocompromised patients are discussed. |
format | Online Article Text |
id | pubmed-7175641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-71756412020-04-22 Infektionen als Notfall der Onkologie: Übersicht über die aktuellen Leitlinien Juarso, Andreas Edwin Kiehl, Malte Buchholz, Markus Weißinger, Florian Wien Klin Mag Infektiologie BACKGROUND: Patients with oncologic diseases, particularly those with hematologic malignancies, are at an increased risk of common infections and unique treatment-related complications with high mortality and morbidity. The annual incidence and prevalence of cancer in Germany is rising. Although modern treatments have generally led to improved survival, increasing age, comorbidities, and frailty of the patients require multidisciplinary strategies for handling complex therapeutic concepts and treatment of the associated complications. METHODS: A selective literature search and guidelines from the European Society for Medical Oncology (ESMO), the German Society of Hematology and Medical Oncology (Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie, DGHO), the Infectious Diseases Working Group of the DGHO (Arbeitsgemeinschaft Infektionen in der Hämatologie und Onkologie, AGIHO), and the American Society of Clinical Oncology (ASCO) formed the basis of this study. CONCLUSION: Recognition of severe infections in cancer patients and their discrimination from treatment-associated complications is a challenge. Neutropenic fever is the most frequent infectious emergency in oncology. Early empiric treatment with broad-spectrum antibiotics and escalated diagnostic strategies are needed to successfully treat this vulnerable patient group. In this article, a range of potentially life-threatening infections in immunocompromised patients are discussed. Springer Vienna 2020-04-22 2020 /pmc/articles/PMC7175641/ /pubmed/32322312 http://dx.doi.org/10.1007/s00740-020-00339-z Text en © Springer-Verlag GmbH Austria, ein Teil von Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Infektiologie Juarso, Andreas Edwin Kiehl, Malte Buchholz, Markus Weißinger, Florian Infektionen als Notfall der Onkologie: Übersicht über die aktuellen Leitlinien |
title | Infektionen als Notfall der Onkologie: Übersicht über die aktuellen Leitlinien |
title_full | Infektionen als Notfall der Onkologie: Übersicht über die aktuellen Leitlinien |
title_fullStr | Infektionen als Notfall der Onkologie: Übersicht über die aktuellen Leitlinien |
title_full_unstemmed | Infektionen als Notfall der Onkologie: Übersicht über die aktuellen Leitlinien |
title_short | Infektionen als Notfall der Onkologie: Übersicht über die aktuellen Leitlinien |
title_sort | infektionen als notfall der onkologie: übersicht über die aktuellen leitlinien |
topic | Infektiologie |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175641/ https://www.ncbi.nlm.nih.gov/pubmed/32322312 http://dx.doi.org/10.1007/s00740-020-00339-z |
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