Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia

The aim of this study was to investigate whether the effect of physical activity on cognitive function in persons with dementia is moderated by patient characteristics as Apolipoprotein E and dementia type. We included 101 individuals with dementia and calculated the reliable change index to determi...

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Detalles Bibliográficos
Autores principales: Uijen, Iris L., Aaronson, Justine A., Karssemeijer, Esther G.A., Olde Rikkert, Marcel G.M., Kessels, Roy P.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175929/
https://www.ncbi.nlm.nih.gov/pubmed/32039840
http://dx.doi.org/10.3233/JAD-190606
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author Uijen, Iris L.
Aaronson, Justine A.
Karssemeijer, Esther G.A.
Olde Rikkert, Marcel G.M.
Kessels, Roy P.C.
author_facet Uijen, Iris L.
Aaronson, Justine A.
Karssemeijer, Esther G.A.
Olde Rikkert, Marcel G.M.
Kessels, Roy P.C.
author_sort Uijen, Iris L.
collection PubMed
description The aim of this study was to investigate whether the effect of physical activity on cognitive function in persons with dementia is moderated by patient characteristics as Apolipoprotein E and dementia type. We included 101 individuals with dementia and calculated the reliable change index to determine the change in global cognition, executive function, episodic memory, working memory, and processing speed before and after a 12-week exercise training. We found a higher treatment-related benefit in episodic memory in persons with non-Alzheimer’s disease compared to persons with Alzheimer’s disease, and in executive function in individuals with better baseline cognitive function.
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spelling pubmed-71759292020-04-28 Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia Uijen, Iris L. Aaronson, Justine A. Karssemeijer, Esther G.A. Olde Rikkert, Marcel G.M. Kessels, Roy P.C. J Alzheimers Dis Short Communication The aim of this study was to investigate whether the effect of physical activity on cognitive function in persons with dementia is moderated by patient characteristics as Apolipoprotein E and dementia type. We included 101 individuals with dementia and calculated the reliable change index to determine the change in global cognition, executive function, episodic memory, working memory, and processing speed before and after a 12-week exercise training. We found a higher treatment-related benefit in episodic memory in persons with non-Alzheimer’s disease compared to persons with Alzheimer’s disease, and in executive function in individuals with better baseline cognitive function. IOS Press 2020-03-24 /pmc/articles/PMC7175929/ /pubmed/32039840 http://dx.doi.org/10.3233/JAD-190606 Text en © 2020 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Uijen, Iris L.
Aaronson, Justine A.
Karssemeijer, Esther G.A.
Olde Rikkert, Marcel G.M.
Kessels, Roy P.C.
Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia
title Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia
title_full Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia
title_fullStr Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia
title_full_unstemmed Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia
title_short Individual Differences in the Effects of Physical Activity on Cognitive Function in People with Mild to Moderate Dementia
title_sort individual differences in the effects of physical activity on cognitive function in people with mild to moderate dementia
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175929/
https://www.ncbi.nlm.nih.gov/pubmed/32039840
http://dx.doi.org/10.3233/JAD-190606
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