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Drosophila NUAK functions with Starvin/BAG3 in autophagic protein turnover

The inability to remove protein aggregates in post-mitotic cells such as muscles or neurons is a cellular hallmark of aging cells and is a key factor in the initiation and progression of protein misfolding diseases. While protein aggregate disorders share common features, the molecular level events...

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Detalles Bibliográficos
Autores principales: Brooks, David, Naeem, Fawwaz, Stetsiv, Marta, Goetting, Samantha C., Bawa, Simranjot, Green, Nicole, Clark, Cheryl, Bashirullah, Arash, Geisbrecht, Erika R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176095/
https://www.ncbi.nlm.nih.gov/pubmed/32320396
http://dx.doi.org/10.1371/journal.pgen.1008700