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Drosophila NUAK functions with Starvin/BAG3 in autophagic protein turnover
The inability to remove protein aggregates in post-mitotic cells such as muscles or neurons is a cellular hallmark of aging cells and is a key factor in the initiation and progression of protein misfolding diseases. While protein aggregate disorders share common features, the molecular level events...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176095/ https://www.ncbi.nlm.nih.gov/pubmed/32320396 http://dx.doi.org/10.1371/journal.pgen.1008700 |