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Epigenetic regulation of defense genes by histone deacetylase1 in human cell line-derived macrophages promotes intracellular survival of Leishmania donovani

Leishmania donovani, an intracellular protozoan parasite upon infection, encounters a range of antimicrobial factors within the host cells. Consequently, the parasite has evolved mechanisms to evade this hostile defense system through inhibition of macrophage activation that, in turn, enables parasi...

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Detalles Bibliográficos
Autores principales: Roy, Gargi, Brar, Harsimran Kaur, Muthuswami, Rohini, Madhubala, Rentala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176143/
https://www.ncbi.nlm.nih.gov/pubmed/32275661
http://dx.doi.org/10.1371/journal.pntd.0008167